ETV5 transcription factor is overexpressed in ovarian cancer and regulates cell adhesion in ovarian cancer cells

Epithelial ovarian cancer is the most lethal gynecological malignancy and the fifth leading cause of cancer deaths in women in the Western world. ETS transcription factors are known to act as positive or negative regulators of the expression of genes that are involved in various biological processes...

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Veröffentlicht in:	International journal of cancer 2012-04, Vol.130 (7), p.1532-1543
Hauptverfasser:	Llauradó, Marta, Abal, Miguel, Castellví, Josep, Cabrera, Sílvia, Gil-Moreno, Antonio, Pérez-Benavente, Asumpció, Colás, Eva, Doll, Andreas, Dolcet, Xavier, Matias-Guiu, Xavier, Vazquez-Levin, Mónica, Reventós, Jaume, Ruiz, Anna
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Apoptosis Apoptosis - genetics Biological and medical sciences Cadherins - genetics Cadherins - metabolism Cancer Carcinoma, Ovarian Epithelial Cell adhesion & migration Cell Adhesion - genetics Cell Growth Processes - genetics Cell Line, Tumor Cell Movement - genetics Cell Survival - genetics DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Down-Regulation ETS transcription factors ETV5 Extracellular Matrix - genetics Extracellular Matrix - metabolism Female Female genital diseases Gene Expression Regulation, Neoplastic - genetics Gene Knockdown Techniques - methods Gynecology. Andrology. Obstetrics Humans Medical research Medical sciences Neoplasm Metastasis Neoplasms, Glandular and Epithelial - genetics Neoplasms, Glandular and Epithelial - metabolism Neoplasms, Glandular and Epithelial - pathology Ovarian cancer Ovarian Neoplasms - genetics Ovarian Neoplasms - metabolism Ovarian Neoplasms - pathology Ovary - metabolism Ovary - pathology Peritoneal Cavity - pathology RNA, Small Interfering - administration & dosage RNA, Small Interfering - genetics Transcription factors Transcription Factors - genetics Transcription Factors - metabolism tumor dissemination Tumors Up-Regulation - genetics
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