Surface shaving as a versatile tool to profile global interactions between human serum proteins and the Staphylococcus aureus cell surface

The human commensal bacterium Staphylococcus aureus is renowned as a causative agent of severe invasive diseases. Upon entering the bloodstream, S. aureus can infect almost every tissue and organ system in the human body. To withstand insults from the immune system upon invasion, several immune‐evas...

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Veröffentlicht in:	Proteomics (Weinheim) 2011-07, Vol.11 (14), p.2921-2930
Hauptverfasser:	Dreisbach, Annette, van der Kooi-Pol, Magdalena M., Otto, Andreas, Gronau, Katrin, Bonarius, Hendrik P. J., Westra, Hans, Groen, Herman, Becher, Dörte, Hecker, Michael, van Dijl, Jan M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alpha-Globulins - chemistry Alpha-Globulins - metabolism Analytical, structural and metabolic biochemistry Animals Bacterial Proteins - chemistry Bacterial Proteins - metabolism Bacteriology Biological and medical sciences Blood Proteins - chemistry Blood Proteins - metabolism Cell Membrane - chemistry Complement Fundamental and applied biological sciences. Psychology Genes Host-pathogen interaction Humans Immune system Immunoglobulin G - chemistry Mass Spectrometry - methods Microbiology Miscellaneous Newman Peptides Peptides - analysis Protein Binding Proteins Staphylococcal Infections - metabolism Staphylococcus Staphylococcus aureus Staphylococcus aureus - chemistry Staphylococcus aureus - cytology Surface Properties Trypsin - metabolism USA300
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