Intestinal Bacterial Colonization Induces Mutualistic Regulatory T Cell Responses

Mammals harbor a dense commensal microbiota in the colon. Regulatory T (Treg) cells are known to limit microbe-triggered intestinal inflammation and the CD4 + T cell compartment is shaped by the presence of particular microbes or bacterial compounds. It is, however, difficult to distinguish whether...

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Veröffentlicht in:	Immunity (Cambridge, Mass.) Mass.), 2011-05, Vol.34 (5), p.794-806
Hauptverfasser:	Geuking, Markus B., Cahenzli, Julia, Lawson, Melissa A.E., Ng, Derek C.K., Slack, Emma, Hapfelmeier, Siegfried, McCoy, Kathy D., Macpherson, Andrew J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptations Adaptive Immunity Animals Bacteria CD4 antigen Cell Proliferation Colon Colon - cytology Colon - immunology Colon - microbiology Colonization Commensals Dextran sulfate Helper cells Homeostasis Immunity, Mucosal Immunology Immunoregulation Inflammation Inflammatory bowel disease Interleukin-10 - immunology Intestine Laboratories Lymphocyte Activation Lymphocytes T Medical research Mice Microscopy Microscopy, Electron, Scanning Microscopy, Electron, Transmission Mutualism Population Rodents T cell receptors T-Lymphocytes, Regulatory - cytology T-Lymphocytes, Regulatory - immunology
Online-Zugang:	Volltext
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