The characterization of gene expression during mouse neural stem cell differentiation in vitro

► Gene expression profiling was performed during short-term differentiation of NSCs. ► Cell cycle-related genes including Ccnb1, Ccnd1 and Ccnd2 were down-regulated. ► BMP and TGF-beta2 signaling pathways were identified by Ingenuity Pathway Analysis. Neural stem cells (NSCs) are tissue-specific, mu...

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Veröffentlicht in:	Neuroscience letters 2012-01, Vol.506 (1), p.50-54
Hauptverfasser:	Park, Ji Hyun, Choi, Mi Ran, Park, Kyoung Sun, Kim, Seung Hyun, Jung, Kyoung Hwa, Chai, Young Gyu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals BMP Cell cycle Cell Differentiation - physiology Cell Proliferation Cells, Cultured Differentiation Embryo, Mammalian Female Gene Expression Regulation, Developmental - physiology Gene Regulatory Networks - physiology Mice Mice, Inbred C57BL Microarray Analysis Nerve Tissue Proteins - genetics Nerve Tissue Proteins - metabolism Neural stem cells Neural Stem Cells - cytology Neural Stem Cells - physiology Neuroglia - metabolism Neurons - metabolism Pregnancy RNA, Messenger - metabolism TGF-beta2 Time Factors
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