Epoxide and Thiirane Toxicity In vitro with the Ciliates Tetrahymena pyriformis: Structural Alerts Indicating Excess Toxicity

The 48 h toxicity of 18 organic narcotics, 13 epoxides, and 2 thiiranes toward the ciliates Tetrahymena pyriformis was determined in terms of 50% growth inhibition EC50. Nominal EC50 was corrected for volatilization and sorption to quantify the freely dissolved compound fraction in solution. The der...

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Veröffentlicht in:	Environmental science & technology 2011-07, Vol.45 (13), p.5812-5819
Hauptverfasser:	Schramm, Franziska, Müller, Andrea, Hammer, Heiko, Paschke, Albrecht, Schüürmann, Gerrit
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal, plant and microbial ecology Applied ecology Aquatic life Biological and medical sciences Ecotoxicology and Human Environmental Health Ecotoxicology, biological effects of pollution Epoxy Compounds - chemistry Epoxy Compounds - metabolism Epoxy Compounds - toxicity Fundamental and applied biological sciences. Psychology General aspects Hydrogen bonds In Vitro Techniques Inhibitory Concentration 50 Models, Chemical Molecular Structure Narcotics - toxicity Proteins Schiff Bases - metabolism Sorption Sulfides - chemistry Sulfides - metabolism Sulfides - toxicity Tetrahymena pyriformis Tetrahymena pyriformis - drug effects Tetrahymena pyriformis - growth & development Toxicity
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