Quantity of clonal cells detected by conventional cytogenetic analysis correlates with bone marrow blasts and survival in myelodysplastic syndromes

Abstract We performed quantitative and qualitative analyses of conventional cytogenetic analysis and interphase FISH results in 87 MDS patients. The quantity of clonal cells for each chromosome of CCA did not correlate with the result of iFISH ( r , range 0.0761–1.0577). The clonal cell percentage i...

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Veröffentlicht in:	Leukemia research 2012-02, Vol.36 (2), p.163-168
Hauptverfasser:	Kim, Miyoung, Chung, Soie, See, Cha Ja, Yoon, Sung-Soo, Kim, Byoung Kook, Kim, Hyun Kyung, Lee, Dong Soon
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Blast Crisis Bone Marrow - pathology Chromosome Aberrations Clonality Clone Cells Conventional cytogenetic analysis Cytogenetic Analysis Female FISH Hematology, Oncology and Palliative Medicine Humans In Situ Hybridization, Fluorescence Interphase Karyotyping Male MDS Middle Aged Myelodysplastic Syndromes - genetics Myelodysplastic Syndromes - mortality Myelodysplastic Syndromes - pathology Prognosis Quantity Survival Rate Young Adult
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