Enhanced immobilization of acidic proteins in the apatite layer via electrostatic interactions in a supersaturated calcium phosphate solution

Artificial materials coated with a protein–apatite composite layer have great potential in clinical applications as a third generation biomaterial. Such composite materials can be prepared by immersing a surface modified substrate into a supersaturated calcium phosphate solution (CP solution: 142 mM...

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Veröffentlicht in:Acta biomaterialia 2011-07, Vol.7 (7), p.2969-2976
Hauptverfasser: Oyane, Ayako, Ootsuka, Teruhisa, Hayama, Kazumi, Sogo, Yu, Ito, Atsuo
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Sprache:eng
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