Limitations of the Standard Agglutination Test for Detecting Patients with Brucella melitensis Bacteremia
The sensitivity of the standard agglutination test (SAT) for detecting brucellosis was determined in 264 Israeli patients from whom a positive blood culture for Brucella melitensis and serology were obtained within±1 week. A SAT titer ≥1:160 had a diagnostic sensitivity of 91.7%, whereas raising the...
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| Veröffentlicht in: | Vector borne and zoonotic diseases (Larchmont, N.Y.) N.Y.), 2011-12, Vol.11 (12), p.1599-1601 |
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| container_title | Vector borne and zoonotic diseases (Larchmont, N.Y.) |
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| creator | Shemesh, Ari A. Yagupsky, Pablo |
| description | The sensitivity of the standard agglutination test (SAT) for detecting brucellosis was determined in 264 Israeli patients from whom a positive blood culture for
Brucella melitensis
and serology were obtained within±1 week. A SAT titer ≥1:160 had a diagnostic sensitivity of 91.7%, whereas raising the cutoff to ≥1:320, as recommended to decrease false-positive rates in endemic areas, reduced the sensitivity to 82.6%. Physicians working in regions endemic for brucellosis should be aware of the limitations of the SAT for detecting patients with the disease. |
| doi_str_mv | 10.1089/vbz.2011.0704 |
| format | Article |
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Brucella melitensis
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and serology were obtained within±1 week. A SAT titer ≥1:160 had a diagnostic sensitivity of 91.7%, whereas raising the cutoff to ≥1:320, as recommended to decrease false-positive rates in endemic areas, reduced the sensitivity to 82.6%. Physicians working in regions endemic for brucellosis should be aware of the limitations of the SAT for detecting patients with the disease.</abstract><cop>United States</cop><pub>Mary Ann Liebert, Inc</pub><pmid>21919731</pmid><doi>10.1089/vbz.2011.0704</doi><tpages>3</tpages></addata></record> |
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| ispartof | Vector borne and zoonotic diseases (Larchmont, N.Y.), 2011-12, Vol.11 (12), p.1599-1601 |
| issn | 1530-3667 1557-7759 |
| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Agglutination Tests - standards Bacteremia - blood Bacteremia - diagnosis Bacteremia - microbiology Brucella melitensis Brucella melitensis - isolation & purification Brucellosis - blood Brucellosis - diagnosis Humans Israel Sensitivity and Specificity Short Communications |
| title | Limitations of the Standard Agglutination Test for Detecting Patients with Brucella melitensis Bacteremia |
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