Novel variants of the qnrB gene, qnrB31 and qnrB32, in Klebsiella pneumoniae

Quinolone resistance in the family Enterobacteriaceae is mostly attributed to the accumulation of mutations in the bacterial enzymes targeted by fluoroquinolones: DNA gyrase and DNA topoisomerase IV. Here we isolated the Klebsiella pneumoniae strains KP3606 and KP4707 from different specimens from 2...

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Veröffentlicht in:	Journal of medical microbiology 2011-12, Vol.60 (12), p.1849-1852
Hauptverfasser:	Wang, Dongguo, Wang, Haibao, Qi, Yongxiao, Liang, Yong, Zhang, Jing, Yu, Lianhua
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Anti-Bacterial Agents - pharmacology Bacteriology Base Sequence Biological and medical sciences DNA Gyrase - genetics DNA topoisomerase DNA topoisomerase IV DNA Topoisomerase IV - genetics DNA, Bacterial - genetics Drug Resistance, Bacterial - genetics Enterobacteriaceae Enzymes Evolution Evolutionary genetics Fluoroquinolones Fundamental and applied biological sciences. Psychology Genes, Bacterial Genetic Variation Hospitals Infectious diseases Klebsiella pneumoniae Klebsiella pneumoniae - drug effects Klebsiella pneumoniae - genetics Klebsiella pneumoniae - isolation & purification Medical sciences Microbial Sensitivity Tests Microbiology Minimum inhibitory concentration Miscellaneous Molecular Sequence Data Mutation Plasmids Quinolones Quinolones - pharmacology Sequence Analysis, DNA
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