Metabolic engineering and classic selection of the yeast Candida famata ( Candida flareri) for construction of strains with enhanced riboflavin production

Currently, the mutant of the flavinogenic yeast Candida famata dep8 isolated by classic mutagenesis and selection is used for industrial riboflavin production. Here we report on construction of a riboflavin overproducing strain of C. famata using a combination of random mutagenesis based on the sele...

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Veröffentlicht in:	Metabolic engineering 2011, Vol.13 (1), p.82-88
Hauptverfasser:	Dmytruk, Kostyantyn V., Yatsyshyn, Valentyna Y., Sybirna, Natalia O., Fedorovych, Daria V., Sibirny, Andriy A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Candida Candida - classification Candida - genetics Candida - metabolism Candida famata Cloning, Molecular Debaryomyces hansenii Fungal Proteins - genetics Fungal Proteins - metabolism Genetic Enhancement - methods Recombinant Proteins - metabolism Riboflavin Riboflavin - biosynthesis Riboflavin - genetics Riboflavin overproducers Signal Transduction - physiology Species Specificity Vitamin B 2 Yeast
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