Direct detection by real-time PCR of ftsI gene mutations affecting MICs of Delta b-lactam agents for Haemophilus influenzae isolates from meningitis

One resistance mechanism of Haemophilus influenzae to ampicillin involves decreased affinity of penicillin-binding protein (PBP) 3 for Delta *b-lactam antibiotics reflecting amino acid substitutions in PBP3 encoded by the ftsI gene. Three amino acid substitutions, Ser385Thr, Arg517His, and Asn526Lys...

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Veröffentlicht in:	Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2011-10, Vol.17 (5), p.671-677
Hauptverfasser:	Kishii, Kozue, Morozumi, Miyuki, Chiba, Naoko, Ono, Akiko, Ubukata, Kimiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Haemophilus influenzae
Online-Zugang:	Volltext
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