Allicin disrupts the cell's electrochemical potential and induces apoptosis in yeast

The volatile substance allicin gives crushed garlic ( Allium sativum) its characteristic odor and is a pro-oxidant that undergoes thiol–disulfide exchange reactions with –SH groups in proteins and glutathione. The antimicrobial activity of allicin is suspected to be due to the oxidative inactivation...

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Veröffentlicht in:Free radical biology & medicine 2010-12, Vol.49 (12), p.1916-1924
Hauptverfasser: Gruhlke, Martin C.H., Portz, Daniela, Stitz, Michael, Anwar, Awais, Schneider, Thomas, Jacob, Claus, Schlaich, Nikolaus L., Slusarenko, Alan J.
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Sprache:eng
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