The enigma of the CLIC proteins: Ion channels, redox proteins, enzymes, scaffolding proteins?

Chloride intracellular channel proteins (CLICs) are distinct from most ion channels in that they have both soluble and integral membrane forms. CLICs are highly conserved in chordates, with six vertebrate paralogues. CLIC-like proteins are found in other metazoans. CLICs form channels in artificial...

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Veröffentlicht in:	FEBS letters 2010-05, Vol.584 (10), p.2093-2101
Hauptverfasser:	Littler, Dene R., Harrop, Stephen J., Goodchild, Sophia C., Phang, Juanita M., Mynott, Andrew V., Jiang, Lele, Valenzuela, Stella M., Mazzanti, Michele, Brown, Louise J., Breit, Samuel N., Curmi, Paul M.G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Membrane - metabolism Chloride Channels - chemistry Chloride Channels - classification Chloride Channels - genetics Chloride Channels - metabolism chloride intracellular channel Chloride intracellular channel protein Chordata CLIC CLIC1 Cytoskeleton - metabolism dehydroascorbate reductase DHAR endoplasmic reticulum Enzymes - chemistry Enzymes - classification Enzymes - genetics Enzymes - metabolism ERM ezrin–moesin–radixin glutaredoxin glutathione glutathione S-transferase Grx GSH GST GST omega GSTO Humans Hydrogen-Ion Concentration Membrane insertion Metazoa Oxidation-Reduction Redox transmembrane Tubulogenesis
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