Photosynthesis driven conversion of carbon dioxide to fatty alcohols and hydrocarbons in cyanobacteria
The production of high value biochemicals and high energy biofuels from sustainable resources through the use of microbial based, green conversion technologies could reduce the dependence on petrochemical resources. However, a sustainable source of carbon and a clean, cost effective method for its c...
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| Veröffentlicht in: | Metabolic engineering 2011-03, Vol.13 (2), p.169-176 |
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| container_title | Metabolic engineering |
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| creator | Tan, Xiaoming Yao, Lun Gao, Qianqian Wang, Weihua Qi, Fengxia Lu, Xuefeng |
| description | The production of high value biochemicals and high energy biofuels from sustainable resources through the use of microbial based, green conversion technologies could reduce the dependence on petrochemical resources. However, a sustainable source of carbon and a clean, cost effective method for its conversion to high quality biofuel products are obstacles that must be overcome. Here we describe the biosynthesis of fatty alcohols in a genetically engineered cyanobacterial system through heterologously expressing fatty acyl-CoA reductase and the effect of environmental stresses on the production of fatty alcohols in the mutant strains. Hydrocarbon production in three representative types of native cyanobacterial model strains and the mutant strain overexpressing acetyl-CoA carboxylase was evaluated. The results of this investigation demonstrate the potential for direct production of high value chemicals and high energy fuels in a single biological system that utilizes solar energy as the energy source and carbon dioxide as the carbon source. |
| doi_str_mv | 10.1016/j.ymben.2011.01.001 |
| format | Article |
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| ispartof | Metabolic engineering, 2011-03, Vol.13 (2), p.169-176 |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Acetyl-CoA Carboxylase - genetics Acetyl-CoA Carboxylase - metabolism Aldehyde Oxidoreductases - genetics Aldehyde Oxidoreductases - metabolism Biofuel Biofuels Carbon Dioxide - metabolism Cyanobacteria Cyanobacteria - genetics Cyanobacteria - metabolism Cyanobacterium Fatty alcohol Fatty Alcohols - metabolism Genetic Engineering Hydrocarbon Hydrocarbons - metabolism Photosynthesis |
| title | Photosynthesis driven conversion of carbon dioxide to fatty alcohols and hydrocarbons in cyanobacteria |
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