Additive effect of zoledronic acid on serum prostate-specific antigen changes for hormone-sensitive prostate cancer patients with bone metastasis treated by combined androgen blockade

Combined androgen blockade is widely used to treat patients with advanced prostate cancer. Recently, zoledronic acid was proven to be effective in preventing skeletal‐related events for prostate cancer patients with bone metastases. Aim of the present study was to assess the effect of adding zoledro...

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Veröffentlicht in:	International journal of urology 2012-02, Vol.19 (2), p.169-173
Hauptverfasser:	Kamiya, Naoto, Suzuki, Hiroyoshi, Endo, Takumi, Takano, Makoto, Yano, Masashi, Naoi, Makito, Nishimi, Daisuke, Kawamura, Koji, Imamoto, Takashi, Ichikawa, Tomohiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Alkaline phosphatase Alkaline Phosphatase - blood Alkaline Phosphatase - drug effects Androgen Antagonists - therapeutic use Androgens Antitumor activity biomarkers Biomarkers, Tumor - blood Bone cancer Bone Density Conservation Agents - therapeutic use bone metastasis Bone Neoplasms - blood Bone Neoplasms - drug therapy Bone Neoplasms - secondary Bone turnover bone turnover marker Collagen Collagen Type I - blood Collagen Type I - drug effects Diphosphonates - therapeutic use Drug Therapy, Combination Humans Imidazoles - therapeutic use Male Metastases Middle Aged Peptides - blood Peptides - drug effects Prostate cancer prostate-specific antigen Prostate-Specific Antigen - blood Prostate-Specific Antigen - drug effects Prostatic Neoplasms - blood Prostatic Neoplasms - drug therapy Prostatic Neoplasms - pathology pyridinoline Zoledronic acid
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