Small bowel adenocarcinoma copy number profiles are more closely related to colorectal than to gastric cancers

Small bowel adenocarcinoma (SBA) is a rare cancer and consequently, the options for clinical trials are limited. As they are treated according to either a colorectal or a gastric cancer regimen and the molecular biology of a tumor is a pivotal determinant for therapy response, chromosomal copy numbe...

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Veröffentlicht in:	Annals of oncology 2012-02, Vol.23 (2), p.367-374
Hauptverfasser:	Haan, J.C., Buffart, T.E., Eijk, P.P., van de Wiel, M.A., van Wieringen, W.N., Howdle, P.D., Mulder, C.J.J., van de Velde, C.J., Quirke, P., Nagtegaal, I.D., van Grieken, N.C.T., Grabsch, H., Meijer, G.A., Ylstra, B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - genetics Antineoplastic agents array comparative genomic hybridization Biological and medical sciences chromosomal copy number aberrations Colorectal Neoplasms - genetics DNA Copy Number Variations formalin-fixed paraffin-embedded Gastroenterology. Liver. Pancreas. Abdomen hierarchical clustering Humans Intestinal Neoplasms - genetics Intestine, Small Medical sciences Microsatellite Repeats Nucleic Acid Hybridization Pharmacology. Drug treatments small bowel adenocarcinoma Stomach Neoplasms - genetics Stomach. Duodenum. Small intestine. Colon. Rectum. Anus treatment Tumors
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