ΔNp63 is regulated by BMP4 signaling and is required for early epidermal development in Xenopus

Background: It has been established in several models that the p63 gene has an important role in the development of the epidermis and its derivatives. In Xenopus, only the ΔNp63 isoform of this gene has been cloned and its role during epidermal development remains unknown. Results: In this work, we...

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Veröffentlicht in:	Developmental dynamics 2012-02, Vol.241 (2), p.257-269
Hauptverfasser:	Tríbulo, Celeste, Guadalupe Barrionuevo, María, Agüero, Tristán H., Sánchez, Sara S., Calcaterra, Nora B., Aybar, Manuel J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals apoptosis Apoptosis - genetics BMP4 Bone Morphogenetic Protein 4 - metabolism epidermis Epidermis - embryology Epidermis - metabolism Gene Expression Regulation, Developmental Phosphoproteins - genetics Signal Transduction specification Trans-Activators - genetics Xenopus laevis - embryology Xenopus laevis - metabolism Xenopus Proteins - genetics Xenopus Proteins - metabolism ΔNp63
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