Validation study of cause of death statistics in Cape Town, South Africa, found poor agreement
Abstract Objective The validity of the underlying cause of death on death notification forms was assessed by comparing it to the underlying cause determined independently from medical records. Study Design and Setting Retrospective study of 703 deaths in two suburbs of Cape Town, South Africa. Two m...
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description | Abstract Objective The validity of the underlying cause of death on death notification forms was assessed by comparing it to the underlying cause determined independently from medical records. Study Design and Setting Retrospective study of 703 deaths in two suburbs of Cape Town, South Africa. Two medical doctors completed a medical review death certificate to validate the registration death certificate for each decedent. Agreement, sensitivity, and positive predictive value were measured for underlying causes of death using the World Health Organization (WHO) mortality tabulation list 1. Results Agreement was poor, with only 55.3% (95% confidence interval [CI]: 51.7, 59.0) of diagnoses matching at WHO mortality tabulation list 1 level. Validity of reported causes of death was poor for HIV, cardiovascular diseases, and diabetes. With correct reporting, the cause-specific mortality fraction for HIV increased from 11.9% to 18.3% (53.6%; 95% CI: 36.9, 77.6), for ischemic heart disease from 3.3% to 7.3% (121.7%; 95% CI: 53.5, 228.7), and for hypertensive diseases from 3.3% to 5.7% (73.9%; 95% CI: 14.4, 167.8). For diabetes, the mortality fraction decreased from 6.0% to 2.3% (−64.3%; 95% CI: −77.1, −37.8) and for ill-defined deaths from 7.4% to 2.3% (−69.2%; 95% CI: −81.0, −51.6). Conclusion Current cause-specific mortality levels should be cautiously interpreted. Death certification training is required to improve the validity of mortality data. |
doi_str_mv | 10.1016/j.jclinepi.2011.08.007 |
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Study Design and Setting Retrospective study of 703 deaths in two suburbs of Cape Town, South Africa. Two medical doctors completed a medical review death certificate to validate the registration death certificate for each decedent. Agreement, sensitivity, and positive predictive value were measured for underlying causes of death using the World Health Organization (WHO) mortality tabulation list 1. Results Agreement was poor, with only 55.3% (95% confidence interval [CI]: 51.7, 59.0) of diagnoses matching at WHO mortality tabulation list 1 level. Validity of reported causes of death was poor for HIV, cardiovascular diseases, and diabetes. With correct reporting, the cause-specific mortality fraction for HIV increased from 11.9% to 18.3% (53.6%; 95% CI: 36.9, 77.6), for ischemic heart disease from 3.3% to 7.3% (121.7%; 95% CI: 53.5, 228.7), and for hypertensive diseases from 3.3% to 5.7% (73.9%; 95% CI: 14.4, 167.8). For diabetes, the mortality fraction decreased from 6.0% to 2.3% (−64.3%; 95% CI: −77.1, −37.8) and for ill-defined deaths from 7.4% to 2.3% (−69.2%; 95% CI: −81.0, −51.6). Conclusion Current cause-specific mortality levels should be cautiously interpreted. Death certification training is required to improve the validity of mortality data.</description><identifier>ISSN: 0895-4356</identifier><identifier>EISSN: 1878-5921</identifier><identifier>DOI: 10.1016/j.jclinepi.2011.08.007</identifier><identifier>PMID: 22169084</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adolescent ; Adult ; Aged ; Biological and medical sciences ; Cardiovascular diseases ; Cause of death ; Cause of Death - trends ; Child ; Child, Preschool ; Death Certificates ; Death notification ; Diabetes ; Diabetes Mellitus - mortality ; Documentation - standards ; Epidemiology ; Female ; Forensic pathology ; General aspects ; HIV Infections - mortality ; Hospitals ; Humans ; Hypertension ; Infant ; Infant, Newborn ; Internal Medicine ; Lung cancer ; Male ; Medical records ; Medical sciences ; Middle Aged ; Miscellaneous ; Mortality ; Myocardial Ischemia - mortality ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Reproducibility of Results ; Respiratory diseases ; Retrospective Studies ; South Africa ; South Africa - epidemiology ; Statistics as Topic ; Suburban Population - statistics & numerical data ; Suburbs ; Validation study ; Vital Statistics ; World Health Organization ; Young Adult</subject><ispartof>Journal of clinical epidemiology, 2012-03, Vol.65 (3), p.309-316</ispartof><rights>Elsevier Inc.</rights><rights>2012 Elsevier Inc.</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2012 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c480t-b0e90fc251200e6426b9036c7c7d1653928ebfeec9d128e51f9db64019bcfc323</citedby><cites>FETCH-LOGICAL-c480t-b0e90fc251200e6426b9036c7c7d1653928ebfeec9d128e51f9db64019bcfc323</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/1033248347?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995,64385,64387,64389,72469</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=25572722$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22169084$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Burger, Elsie H</creatorcontrib><creatorcontrib>Groenewald, Pam</creatorcontrib><creatorcontrib>Bradshaw, D</creatorcontrib><creatorcontrib>Ward, Alison M</creatorcontrib><creatorcontrib>Yudkin, Patricia L</creatorcontrib><creatorcontrib>Volmink, Jimmy</creatorcontrib><title>Validation study of cause of death statistics in Cape Town, South Africa, found poor agreement</title><title>Journal of clinical epidemiology</title><addtitle>J Clin Epidemiol</addtitle><description>Abstract Objective The validity of the underlying cause of death on death notification forms was assessed by comparing it to the underlying cause determined independently from medical records. Study Design and Setting Retrospective study of 703 deaths in two suburbs of Cape Town, South Africa. Two medical doctors completed a medical review death certificate to validate the registration death certificate for each decedent. Agreement, sensitivity, and positive predictive value were measured for underlying causes of death using the World Health Organization (WHO) mortality tabulation list 1. Results Agreement was poor, with only 55.3% (95% confidence interval [CI]: 51.7, 59.0) of diagnoses matching at WHO mortality tabulation list 1 level. Validity of reported causes of death was poor for HIV, cardiovascular diseases, and diabetes. With correct reporting, the cause-specific mortality fraction for HIV increased from 11.9% to 18.3% (53.6%; 95% CI: 36.9, 77.6), for ischemic heart disease from 3.3% to 7.3% (121.7%; 95% CI: 53.5, 228.7), and for hypertensive diseases from 3.3% to 5.7% (73.9%; 95% CI: 14.4, 167.8). For diabetes, the mortality fraction decreased from 6.0% to 2.3% (−64.3%; 95% CI: −77.1, −37.8) and for ill-defined deaths from 7.4% to 2.3% (−69.2%; 95% CI: −81.0, −51.6). Conclusion Current cause-specific mortality levels should be cautiously interpreted. Death certification training is required to improve the validity of mortality data.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Cardiovascular diseases</subject><subject>Cause of death</subject><subject>Cause of Death - trends</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Death Certificates</subject><subject>Death notification</subject><subject>Diabetes</subject><subject>Diabetes Mellitus - mortality</subject><subject>Documentation - standards</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Forensic pathology</subject><subject>General aspects</subject><subject>HIV Infections - mortality</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Hypertension</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Internal Medicine</subject><subject>Lung cancer</subject><subject>Male</subject><subject>Medical records</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Miscellaneous</subject><subject>Mortality</subject><subject>Myocardial Ischemia - mortality</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Reproducibility of Results</subject><subject>Respiratory diseases</subject><subject>Retrospective Studies</subject><subject>South Africa</subject><subject>South Africa - epidemiology</subject><subject>Statistics as Topic</subject><subject>Suburban Population - statistics & numerical data</subject><subject>Suburbs</subject><subject>Validation study</subject><subject>Vital Statistics</subject><subject>World Health Organization</subject><subject>Young Adult</subject><issn>0895-4356</issn><issn>1878-5921</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkk1v1DAQhi0EotvCX6giIcSlCWMntpMLolqVD6kShxaOWI4zAYesndoJaP89jnZLpV44eeR55tXMvEPIOYWCAhVvh2Iwo3U42YIBpQXUBYB8Qja0lnXOG0afkg3UDc-rkosTchrjAEAlSP6cnDBGRQN1tSHfv-nRdnq23mVxXrp95vvM6CXiGnSo55_pP-XjbE3MrMu2esLs1v9xF9mNX1L6sg_W6Ius94vrssn7kOkfAXGHbn5BnvV6jPjy-J6Rrx-ubref8usvHz9vL69zU9Uw5y1gA71hnDIAFBUTbQOlMNLIjgpeNqzGtkc0TUdTyGnfdK2ogDat6U3JyjPy5qA7BX-3YJzVzkaD46gd-iWqhkou6xJ4Il89Ige_BJeaUxTKklV1WclEiQNlgo8xYK-mYHc67BOkVgPUoO4NUKsBCmqVDEiF50f5pd1h96_sfuMJeH0EdDR67IN2xsYHjnPJJFsnen_gMK3tt8WgorHoDHY2oJlV5-3_e3n3SGKlklfjL9xjfJhbRaZA3aznsl4LpQBMUFn-Be3FuvA</recordid><startdate>20120301</startdate><enddate>20120301</enddate><creator>Burger, Elsie H</creator><creator>Groenewald, Pam</creator><creator>Bradshaw, D</creator><creator>Ward, Alison M</creator><creator>Yudkin, Patricia L</creator><creator>Volmink, Jimmy</creator><general>Elsevier Inc</general><general>Elsevier</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7QP</scope><scope>7RV</scope><scope>7T2</scope><scope>7T7</scope><scope>7TK</scope><scope>7U7</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88C</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>M2O</scope><scope>M7N</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20120301</creationdate><title>Validation study of cause of death statistics in Cape Town, South Africa, found poor agreement</title><author>Burger, Elsie H ; Groenewald, Pam ; Bradshaw, D ; Ward, Alison M ; Yudkin, Patricia L ; Volmink, Jimmy</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c480t-b0e90fc251200e6426b9036c7c7d1653928ebfeec9d128e51f9db64019bcfc323</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Cardiovascular diseases</topic><topic>Cause of death</topic><topic>Cause of Death - trends</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Death Certificates</topic><topic>Death notification</topic><topic>Diabetes</topic><topic>Diabetes Mellitus - mortality</topic><topic>Documentation - standards</topic><topic>Epidemiology</topic><topic>Female</topic><topic>Forensic pathology</topic><topic>General aspects</topic><topic>HIV Infections - mortality</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Hypertension</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Internal Medicine</topic><topic>Lung cancer</topic><topic>Male</topic><topic>Medical records</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Miscellaneous</topic><topic>Mortality</topic><topic>Myocardial Ischemia - mortality</topic><topic>Public health. 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Hygiene-occupational medicine</topic><topic>Reproducibility of Results</topic><topic>Respiratory diseases</topic><topic>Retrospective Studies</topic><topic>South Africa</topic><topic>South Africa - epidemiology</topic><topic>Statistics as Topic</topic><topic>Suburban Population - statistics & numerical data</topic><topic>Suburbs</topic><topic>Validation study</topic><topic>Vital Statistics</topic><topic>World Health Organization</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Burger, Elsie H</creatorcontrib><creatorcontrib>Groenewald, Pam</creatorcontrib><creatorcontrib>Bradshaw, D</creatorcontrib><creatorcontrib>Ward, Alison M</creatorcontrib><creatorcontrib>Yudkin, Patricia L</creatorcontrib><creatorcontrib>Volmink, Jimmy</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Proquest Nursing & Allied Health Source</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Healthcare Administration Database (Alumni)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of clinical epidemiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Burger, Elsie H</au><au>Groenewald, Pam</au><au>Bradshaw, D</au><au>Ward, Alison M</au><au>Yudkin, Patricia L</au><au>Volmink, Jimmy</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Validation study of cause of death statistics in Cape Town, South Africa, found poor agreement</atitle><jtitle>Journal of clinical epidemiology</jtitle><addtitle>J Clin Epidemiol</addtitle><date>2012-03-01</date><risdate>2012</risdate><volume>65</volume><issue>3</issue><spage>309</spage><epage>316</epage><pages>309-316</pages><issn>0895-4356</issn><eissn>1878-5921</eissn><abstract>Abstract Objective The validity of the underlying cause of death on death notification forms was assessed by comparing it to the underlying cause determined independently from medical records. Study Design and Setting Retrospective study of 703 deaths in two suburbs of Cape Town, South Africa. Two medical doctors completed a medical review death certificate to validate the registration death certificate for each decedent. Agreement, sensitivity, and positive predictive value were measured for underlying causes of death using the World Health Organization (WHO) mortality tabulation list 1. Results Agreement was poor, with only 55.3% (95% confidence interval [CI]: 51.7, 59.0) of diagnoses matching at WHO mortality tabulation list 1 level. Validity of reported causes of death was poor for HIV, cardiovascular diseases, and diabetes. With correct reporting, the cause-specific mortality fraction for HIV increased from 11.9% to 18.3% (53.6%; 95% CI: 36.9, 77.6), for ischemic heart disease from 3.3% to 7.3% (121.7%; 95% CI: 53.5, 228.7), and for hypertensive diseases from 3.3% to 5.7% (73.9%; 95% CI: 14.4, 167.8). For diabetes, the mortality fraction decreased from 6.0% to 2.3% (−64.3%; 95% CI: −77.1, −37.8) and for ill-defined deaths from 7.4% to 2.3% (−69.2%; 95% CI: −81.0, −51.6). Conclusion Current cause-specific mortality levels should be cautiously interpreted. Death certification training is required to improve the validity of mortality data.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>22169084</pmid><doi>10.1016/j.jclinepi.2011.08.007</doi><tpages>8</tpages></addata></record> |
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subjects | Adolescent Adult Aged Biological and medical sciences Cardiovascular diseases Cause of death Cause of Death - trends Child Child, Preschool Death Certificates Death notification Diabetes Diabetes Mellitus - mortality Documentation - standards Epidemiology Female Forensic pathology General aspects HIV Infections - mortality Hospitals Humans Hypertension Infant Infant, Newborn Internal Medicine Lung cancer Male Medical records Medical sciences Middle Aged Miscellaneous Mortality Myocardial Ischemia - mortality Public health. Hygiene Public health. Hygiene-occupational medicine Reproducibility of Results Respiratory diseases Retrospective Studies South Africa South Africa - epidemiology Statistics as Topic Suburban Population - statistics & numerical data Suburbs Validation study Vital Statistics World Health Organization Young Adult |
title | Validation study of cause of death statistics in Cape Town, South Africa, found poor agreement |
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