Profiling of Epstein‐Barr virus‐encoded microRNAs in nasopharyngeal carcinoma reveals potential biomarkers and oncomirs

BACKGROUND: Epstein‐Barr virus (EBV) microRNAs are abundant in nasopharyngeal carcinoma (NPC) tumors. With recent advances in serum microRNA detection, the distinct presence of EBV microRNAs in serum could aid in screening endemic regions for NPC. A proposed network of genes targeted by these microR...

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Veröffentlicht in:	Cancer 2012-02, Vol.118 (3), p.698-710
Hauptverfasser:	Wong, Alissa Michelle Go, Kong, Kar Lok, Tsang, Janice Wing Hang, Kwong, Dora Lai Wan, Guan, Xin‐Yuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences biological marker Biomarkers, Tumor - genetics Blotting, Western Case-Control Studies Epstein-Barr Virus Infections - blood Epstein-Barr Virus Infections - genetics Epstein-Barr Virus Infections - virology Epstein‐Barr Virus Female Gene Expression Profiling Herpesvirus 4, Human - genetics Herpesvirus 4, Human - isolation & purification Humans Infectious diseases Male Medical sciences microRNAs MicroRNAs - blood MicroRNAs - genetics Middle Aged nasopharyngeal neoplasms Nasopharyngeal Neoplasms - blood Nasopharyngeal Neoplasms - genetics Nasopharyngeal Neoplasms - virology Oligonucleotide Array Sequence Analysis Oncogenes Prognosis Real-Time Polymerase Chain Reaction RNA, Viral - blood RNA, Viral - genetics screening Tumors Viral diseases
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