Assessment of work instability in spondyloarthritis: a cross-sectional study using the ankylosing spondylitis work instability scale

Objectives. Work status is an important outcome in SpA. The objective was to assess work instability and its determinants in a cohort of patients with SpA, using the AS-work instability scale (AS-WIS). Methods. We performed a cross-sectional monocentre study. Patients were definite SpA patients with...

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Veröffentlicht in:Rheumatology (Oxford, England) England), 2012-02, Vol.51 (2), p.333-337
Hauptverfasser: Fabreguet, Isabelle, Koumakis, Eugénie, Burki, Vincent, Durnez, Anne, Elhai, Muriel, Meyer, Magali, Paternotte, Simon, Payet, Judith, Roure, Fanny, Fautrel, Bruno, Dougados, Maxime, Gossec, Laure
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container_issue 2
container_start_page 333
container_title Rheumatology (Oxford, England)
container_volume 51
creator Fabreguet, Isabelle
Koumakis, Eugénie
Burki, Vincent
Durnez, Anne
Elhai, Muriel
Meyer, Magali
Paternotte, Simon
Payet, Judith
Roure, Fanny
Fautrel, Bruno
Dougados, Maxime
Gossec, Laure
description Objectives. Work status is an important outcome in SpA. The objective was to assess work instability and its determinants in a cohort of patients with SpA, using the AS-work instability scale (AS-WIS). Methods. We performed a cross-sectional monocentre study. Patients were definite SpA patients with paid work. Work instability was measured by the AS-WIS. Its determinants were assessed by correlations with SpA scores (BASDAI, BASFI and patient's global assessment) and patients with low work instability (AS-WIS score 
doi_str_mv 10.1093/rheumatology/ker319
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Work status is an important outcome in SpA. The objective was to assess work instability and its determinants in a cohort of patients with SpA, using the AS-work instability scale (AS-WIS). Methods. We performed a cross-sectional monocentre study. Patients were definite SpA patients with paid work. Work instability was measured by the AS-WIS. Its determinants were assessed by correlations with SpA scores (BASDAI, BASFI and patient's global assessment) and patients with low work instability (AS-WIS score &lt; 11) were compared with those with moderate to high instability, through backward logistic regression. Results. In all, 156 patients were assessed: mean (s.d.) age 41 (11) years, mean disease duration 15 (11) years; 71 (45.5%) were on TNF blockers. The mean AS-WIS score was 9.5 (5.5); 55 (35%) patients had moderate and 8 (5%) patients had high work instability. Correlations of the AS-WIS score with SpA scores were significant but moderate (BASDAI R = 0.42, BASFI R = 0.41, patient's global assessment R = 0.53; P &lt; 0.0001). In multivariate analysis, high patient's global assessment was the only element associated with moderate to high work instability; demographic characteristics and treatments were not significant elements. Conclusion. Work instability was found to be high and its main determinant was patient's global assessment. The predictive validity of the AS-WIS in terms of job retention should be further assessed.</description><identifier>ISSN: 1462-0324</identifier><identifier>EISSN: 1462-0332</identifier><identifier>DOI: 10.1093/rheumatology/ker319</identifier><identifier>PMID: 22087013</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Adult ; Cohort Studies ; Cross-Sectional Studies ; Disability Evaluation ; Employment - statistics &amp; numerical data ; Female ; Humans ; Male ; Middle Aged ; Reproducibility of Results ; Sickness Impact Profile ; Spondylitis, Ankylosing - diagnosis ; Spondylitis, Ankylosing - physiopathology</subject><ispartof>Rheumatology (Oxford, England), 2012-02, Vol.51 (2), p.333-337</ispartof><rights>The Author 2011. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oup.com 2011</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c388t-6f33b91eb21aeba7360b1ab2d82ce93ae90db06b7ae231f5f6d17f3b4c20cf263</citedby><cites>FETCH-LOGICAL-c388t-6f33b91eb21aeba7360b1ab2d82ce93ae90db06b7ae231f5f6d17f3b4c20cf263</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,1584,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22087013$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fabreguet, Isabelle</creatorcontrib><creatorcontrib>Koumakis, Eugénie</creatorcontrib><creatorcontrib>Burki, Vincent</creatorcontrib><creatorcontrib>Durnez, Anne</creatorcontrib><creatorcontrib>Elhai, Muriel</creatorcontrib><creatorcontrib>Meyer, Magali</creatorcontrib><creatorcontrib>Paternotte, Simon</creatorcontrib><creatorcontrib>Payet, Judith</creatorcontrib><creatorcontrib>Roure, Fanny</creatorcontrib><creatorcontrib>Fautrel, Bruno</creatorcontrib><creatorcontrib>Dougados, Maxime</creatorcontrib><creatorcontrib>Gossec, Laure</creatorcontrib><title>Assessment of work instability in spondyloarthritis: a cross-sectional study using the ankylosing spondylitis work instability scale</title><title>Rheumatology (Oxford, England)</title><addtitle>Rheumatology (Oxford)</addtitle><description>Objectives. Work status is an important outcome in SpA. The objective was to assess work instability and its determinants in a cohort of patients with SpA, using the AS-work instability scale (AS-WIS). Methods. We performed a cross-sectional monocentre study. Patients were definite SpA patients with paid work. Work instability was measured by the AS-WIS. Its determinants were assessed by correlations with SpA scores (BASDAI, BASFI and patient's global assessment) and patients with low work instability (AS-WIS score &lt; 11) were compared with those with moderate to high instability, through backward logistic regression. Results. In all, 156 patients were assessed: mean (s.d.) age 41 (11) years, mean disease duration 15 (11) years; 71 (45.5%) were on TNF blockers. The mean AS-WIS score was 9.5 (5.5); 55 (35%) patients had moderate and 8 (5%) patients had high work instability. Correlations of the AS-WIS score with SpA scores were significant but moderate (BASDAI R = 0.42, BASFI R = 0.41, patient's global assessment R = 0.53; P &lt; 0.0001). In multivariate analysis, high patient's global assessment was the only element associated with moderate to high work instability; demographic characteristics and treatments were not significant elements. Conclusion. Work instability was found to be high and its main determinant was patient's global assessment. The predictive validity of the AS-WIS in terms of job retention should be further assessed.</description><subject>Adult</subject><subject>Cohort Studies</subject><subject>Cross-Sectional Studies</subject><subject>Disability Evaluation</subject><subject>Employment - statistics &amp; numerical data</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Reproducibility of Results</subject><subject>Sickness Impact Profile</subject><subject>Spondylitis, Ankylosing - diagnosis</subject><subject>Spondylitis, Ankylosing - physiopathology</subject><issn>1462-0324</issn><issn>1462-0332</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkE1Lw0AQhhdRbK3-AkH25intfrT58FaKX1Dwouewm0zatUm27myQ3P3hpk0tghdPMwPP88K8hFxzNuYskRO3hqZS3pZ21U424CRPTsiQT0MRMCnF6XEX0wG5QHxnjM24jM_JQAgWR4zLIfmaIwJiBbWntqCf1m2oqdErbUrj226nuLV13pZWOb92xhu8o4pmziIGCJk3tlYlRd_kLW3Q1Cvq10BVvemU_Xnwd-bffMxUCZfkrFAlwtVhjsjbw_3r4ilYvjw-L-bLIJNx7IOwkFInHLTgCrSKZMg0V1rkscggkQoSlmsW6kiBkLyYFWHOo0LqaSZYVohQjshtn7t19qMB9GllMIOyVDXYBtOER7MomjLRkbIn9386KNKtM5VybcpZums__d1-2rffWTeH_EZXkB-dn7o7YNwDttn-K_Ebp1WbXg</recordid><startdate>201202</startdate><enddate>201202</enddate><creator>Fabreguet, Isabelle</creator><creator>Koumakis, Eugénie</creator><creator>Burki, Vincent</creator><creator>Durnez, Anne</creator><creator>Elhai, Muriel</creator><creator>Meyer, Magali</creator><creator>Paternotte, Simon</creator><creator>Payet, Judith</creator><creator>Roure, Fanny</creator><creator>Fautrel, Bruno</creator><creator>Dougados, Maxime</creator><creator>Gossec, Laure</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201202</creationdate><title>Assessment of work instability in spondyloarthritis: a cross-sectional study using the ankylosing spondylitis work instability scale</title><author>Fabreguet, Isabelle ; Koumakis, Eugénie ; Burki, Vincent ; Durnez, Anne ; Elhai, Muriel ; Meyer, Magali ; Paternotte, Simon ; Payet, Judith ; Roure, Fanny ; Fautrel, Bruno ; Dougados, Maxime ; Gossec, Laure</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c388t-6f33b91eb21aeba7360b1ab2d82ce93ae90db06b7ae231f5f6d17f3b4c20cf263</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adult</topic><topic>Cohort Studies</topic><topic>Cross-Sectional Studies</topic><topic>Disability Evaluation</topic><topic>Employment - statistics &amp; numerical data</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Reproducibility of Results</topic><topic>Sickness Impact Profile</topic><topic>Spondylitis, Ankylosing - diagnosis</topic><topic>Spondylitis, Ankylosing - physiopathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fabreguet, Isabelle</creatorcontrib><creatorcontrib>Koumakis, Eugénie</creatorcontrib><creatorcontrib>Burki, Vincent</creatorcontrib><creatorcontrib>Durnez, Anne</creatorcontrib><creatorcontrib>Elhai, Muriel</creatorcontrib><creatorcontrib>Meyer, Magali</creatorcontrib><creatorcontrib>Paternotte, Simon</creatorcontrib><creatorcontrib>Payet, Judith</creatorcontrib><creatorcontrib>Roure, Fanny</creatorcontrib><creatorcontrib>Fautrel, Bruno</creatorcontrib><creatorcontrib>Dougados, Maxime</creatorcontrib><creatorcontrib>Gossec, Laure</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Rheumatology (Oxford, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fabreguet, Isabelle</au><au>Koumakis, Eugénie</au><au>Burki, Vincent</au><au>Durnez, Anne</au><au>Elhai, Muriel</au><au>Meyer, Magali</au><au>Paternotte, Simon</au><au>Payet, Judith</au><au>Roure, Fanny</au><au>Fautrel, Bruno</au><au>Dougados, Maxime</au><au>Gossec, Laure</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Assessment of work instability in spondyloarthritis: a cross-sectional study using the ankylosing spondylitis work instability scale</atitle><jtitle>Rheumatology (Oxford, England)</jtitle><addtitle>Rheumatology (Oxford)</addtitle><date>2012-02</date><risdate>2012</risdate><volume>51</volume><issue>2</issue><spage>333</spage><epage>337</epage><pages>333-337</pages><issn>1462-0324</issn><eissn>1462-0332</eissn><abstract>Objectives. Work status is an important outcome in SpA. The objective was to assess work instability and its determinants in a cohort of patients with SpA, using the AS-work instability scale (AS-WIS). Methods. We performed a cross-sectional monocentre study. Patients were definite SpA patients with paid work. Work instability was measured by the AS-WIS. Its determinants were assessed by correlations with SpA scores (BASDAI, BASFI and patient's global assessment) and patients with low work instability (AS-WIS score &lt; 11) were compared with those with moderate to high instability, through backward logistic regression. Results. In all, 156 patients were assessed: mean (s.d.) age 41 (11) years, mean disease duration 15 (11) years; 71 (45.5%) were on TNF blockers. The mean AS-WIS score was 9.5 (5.5); 55 (35%) patients had moderate and 8 (5%) patients had high work instability. Correlations of the AS-WIS score with SpA scores were significant but moderate (BASDAI R = 0.42, BASFI R = 0.41, patient's global assessment R = 0.53; P &lt; 0.0001). In multivariate analysis, high patient's global assessment was the only element associated with moderate to high work instability; demographic characteristics and treatments were not significant elements. Conclusion. Work instability was found to be high and its main determinant was patient's global assessment. The predictive validity of the AS-WIS in terms of job retention should be further assessed.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>22087013</pmid><doi>10.1093/rheumatology/ker319</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record>
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subjects Adult
Cohort Studies
Cross-Sectional Studies
Disability Evaluation
Employment - statistics & numerical data
Female
Humans
Male
Middle Aged
Reproducibility of Results
Sickness Impact Profile
Spondylitis, Ankylosing - diagnosis
Spondylitis, Ankylosing - physiopathology
title Assessment of work instability in spondyloarthritis: a cross-sectional study using the ankylosing spondylitis work instability scale
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