Assessment of work instability in spondyloarthritis: a cross-sectional study using the ankylosing spondylitis work instability scale
Objectives. Work status is an important outcome in SpA. The objective was to assess work instability and its determinants in a cohort of patients with SpA, using the AS-work instability scale (AS-WIS). Methods. We performed a cross-sectional monocentre study. Patients were definite SpA patients with...
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Veröffentlicht in: | Rheumatology (Oxford, England) England), 2012-02, Vol.51 (2), p.333-337 |
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creator | Fabreguet, Isabelle Koumakis, Eugénie Burki, Vincent Durnez, Anne Elhai, Muriel Meyer, Magali Paternotte, Simon Payet, Judith Roure, Fanny Fautrel, Bruno Dougados, Maxime Gossec, Laure |
description | Objectives. Work status is an important outcome in SpA. The objective was to assess work instability and its determinants in a cohort of patients with SpA, using the AS-work instability scale (AS-WIS).
Methods. We performed a cross-sectional monocentre study. Patients were definite SpA patients with paid work. Work instability was measured by the AS-WIS. Its determinants were assessed by correlations with SpA scores (BASDAI, BASFI and patient's global assessment) and patients with low work instability (AS-WIS score |
doi_str_mv | 10.1093/rheumatology/ker319 |
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Methods. We performed a cross-sectional monocentre study. Patients were definite SpA patients with paid work. Work instability was measured by the AS-WIS. Its determinants were assessed by correlations with SpA scores (BASDAI, BASFI and patient's global assessment) and patients with low work instability (AS-WIS score < 11) were compared with those with moderate to high instability, through backward logistic regression.
Results. In all, 156 patients were assessed: mean (s.d.) age 41 (11) years, mean disease duration 15 (11) years; 71 (45.5%) were on TNF blockers. The mean AS-WIS score was 9.5 (5.5); 55 (35%) patients had moderate and 8 (5%) patients had high work instability. Correlations of the AS-WIS score with SpA scores were significant but moderate (BASDAI R = 0.42, BASFI R = 0.41, patient's global assessment R = 0.53; P < 0.0001). In multivariate analysis, high patient's global assessment was the only element associated with moderate to high work instability; demographic characteristics and treatments were not significant elements.
Conclusion. Work instability was found to be high and its main determinant was patient's global assessment. The predictive validity of the AS-WIS in terms of job retention should be further assessed.</description><identifier>ISSN: 1462-0324</identifier><identifier>EISSN: 1462-0332</identifier><identifier>DOI: 10.1093/rheumatology/ker319</identifier><identifier>PMID: 22087013</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Adult ; Cohort Studies ; Cross-Sectional Studies ; Disability Evaluation ; Employment - statistics & numerical data ; Female ; Humans ; Male ; Middle Aged ; Reproducibility of Results ; Sickness Impact Profile ; Spondylitis, Ankylosing - diagnosis ; Spondylitis, Ankylosing - physiopathology</subject><ispartof>Rheumatology (Oxford, England), 2012-02, Vol.51 (2), p.333-337</ispartof><rights>The Author 2011. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oup.com 2011</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c388t-6f33b91eb21aeba7360b1ab2d82ce93ae90db06b7ae231f5f6d17f3b4c20cf263</citedby><cites>FETCH-LOGICAL-c388t-6f33b91eb21aeba7360b1ab2d82ce93ae90db06b7ae231f5f6d17f3b4c20cf263</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,1584,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22087013$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fabreguet, Isabelle</creatorcontrib><creatorcontrib>Koumakis, Eugénie</creatorcontrib><creatorcontrib>Burki, Vincent</creatorcontrib><creatorcontrib>Durnez, Anne</creatorcontrib><creatorcontrib>Elhai, Muriel</creatorcontrib><creatorcontrib>Meyer, Magali</creatorcontrib><creatorcontrib>Paternotte, Simon</creatorcontrib><creatorcontrib>Payet, Judith</creatorcontrib><creatorcontrib>Roure, Fanny</creatorcontrib><creatorcontrib>Fautrel, Bruno</creatorcontrib><creatorcontrib>Dougados, Maxime</creatorcontrib><creatorcontrib>Gossec, Laure</creatorcontrib><title>Assessment of work instability in spondyloarthritis: a cross-sectional study using the ankylosing spondylitis work instability scale</title><title>Rheumatology (Oxford, England)</title><addtitle>Rheumatology (Oxford)</addtitle><description>Objectives. Work status is an important outcome in SpA. The objective was to assess work instability and its determinants in a cohort of patients with SpA, using the AS-work instability scale (AS-WIS).
Methods. We performed a cross-sectional monocentre study. Patients were definite SpA patients with paid work. Work instability was measured by the AS-WIS. Its determinants were assessed by correlations with SpA scores (BASDAI, BASFI and patient's global assessment) and patients with low work instability (AS-WIS score < 11) were compared with those with moderate to high instability, through backward logistic regression.
Results. In all, 156 patients were assessed: mean (s.d.) age 41 (11) years, mean disease duration 15 (11) years; 71 (45.5%) were on TNF blockers. The mean AS-WIS score was 9.5 (5.5); 55 (35%) patients had moderate and 8 (5%) patients had high work instability. Correlations of the AS-WIS score with SpA scores were significant but moderate (BASDAI R = 0.42, BASFI R = 0.41, patient's global assessment R = 0.53; P < 0.0001). In multivariate analysis, high patient's global assessment was the only element associated with moderate to high work instability; demographic characteristics and treatments were not significant elements.
Conclusion. Work instability was found to be high and its main determinant was patient's global assessment. The predictive validity of the AS-WIS in terms of job retention should be further assessed.</description><subject>Adult</subject><subject>Cohort Studies</subject><subject>Cross-Sectional Studies</subject><subject>Disability Evaluation</subject><subject>Employment - statistics & numerical data</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Reproducibility of Results</subject><subject>Sickness Impact Profile</subject><subject>Spondylitis, Ankylosing - diagnosis</subject><subject>Spondylitis, Ankylosing - physiopathology</subject><issn>1462-0324</issn><issn>1462-0332</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkE1Lw0AQhhdRbK3-AkH25intfrT58FaKX1Dwouewm0zatUm27myQ3P3hpk0tghdPMwPP88K8hFxzNuYskRO3hqZS3pZ21U424CRPTsiQT0MRMCnF6XEX0wG5QHxnjM24jM_JQAgWR4zLIfmaIwJiBbWntqCf1m2oqdErbUrj226nuLV13pZWOb92xhu8o4pmziIGCJk3tlYlRd_kLW3Q1Cvq10BVvemU_Xnwd-bffMxUCZfkrFAlwtVhjsjbw_3r4ilYvjw-L-bLIJNx7IOwkFInHLTgCrSKZMg0V1rkscggkQoSlmsW6kiBkLyYFWHOo0LqaSZYVohQjshtn7t19qMB9GllMIOyVDXYBtOER7MomjLRkbIn9386KNKtM5VybcpZums__d1-2rffWTeH_EZXkB-dn7o7YNwDttn-K_Ebp1WbXg</recordid><startdate>201202</startdate><enddate>201202</enddate><creator>Fabreguet, Isabelle</creator><creator>Koumakis, Eugénie</creator><creator>Burki, Vincent</creator><creator>Durnez, Anne</creator><creator>Elhai, Muriel</creator><creator>Meyer, Magali</creator><creator>Paternotte, Simon</creator><creator>Payet, Judith</creator><creator>Roure, Fanny</creator><creator>Fautrel, Bruno</creator><creator>Dougados, Maxime</creator><creator>Gossec, Laure</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201202</creationdate><title>Assessment of work instability in spondyloarthritis: a cross-sectional study using the ankylosing spondylitis work instability scale</title><author>Fabreguet, Isabelle ; Koumakis, Eugénie ; Burki, Vincent ; Durnez, Anne ; Elhai, Muriel ; Meyer, Magali ; Paternotte, Simon ; Payet, Judith ; Roure, Fanny ; Fautrel, Bruno ; Dougados, Maxime ; Gossec, Laure</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c388t-6f33b91eb21aeba7360b1ab2d82ce93ae90db06b7ae231f5f6d17f3b4c20cf263</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adult</topic><topic>Cohort Studies</topic><topic>Cross-Sectional Studies</topic><topic>Disability Evaluation</topic><topic>Employment - statistics & numerical data</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Reproducibility of Results</topic><topic>Sickness Impact Profile</topic><topic>Spondylitis, Ankylosing - diagnosis</topic><topic>Spondylitis, Ankylosing - physiopathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fabreguet, Isabelle</creatorcontrib><creatorcontrib>Koumakis, Eugénie</creatorcontrib><creatorcontrib>Burki, Vincent</creatorcontrib><creatorcontrib>Durnez, Anne</creatorcontrib><creatorcontrib>Elhai, Muriel</creatorcontrib><creatorcontrib>Meyer, Magali</creatorcontrib><creatorcontrib>Paternotte, Simon</creatorcontrib><creatorcontrib>Payet, Judith</creatorcontrib><creatorcontrib>Roure, Fanny</creatorcontrib><creatorcontrib>Fautrel, Bruno</creatorcontrib><creatorcontrib>Dougados, Maxime</creatorcontrib><creatorcontrib>Gossec, Laure</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Rheumatology (Oxford, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fabreguet, Isabelle</au><au>Koumakis, Eugénie</au><au>Burki, Vincent</au><au>Durnez, Anne</au><au>Elhai, Muriel</au><au>Meyer, Magali</au><au>Paternotte, Simon</au><au>Payet, Judith</au><au>Roure, Fanny</au><au>Fautrel, Bruno</au><au>Dougados, Maxime</au><au>Gossec, Laure</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Assessment of work instability in spondyloarthritis: a cross-sectional study using the ankylosing spondylitis work instability scale</atitle><jtitle>Rheumatology (Oxford, England)</jtitle><addtitle>Rheumatology (Oxford)</addtitle><date>2012-02</date><risdate>2012</risdate><volume>51</volume><issue>2</issue><spage>333</spage><epage>337</epage><pages>333-337</pages><issn>1462-0324</issn><eissn>1462-0332</eissn><abstract>Objectives. Work status is an important outcome in SpA. The objective was to assess work instability and its determinants in a cohort of patients with SpA, using the AS-work instability scale (AS-WIS).
Methods. We performed a cross-sectional monocentre study. Patients were definite SpA patients with paid work. Work instability was measured by the AS-WIS. Its determinants were assessed by correlations with SpA scores (BASDAI, BASFI and patient's global assessment) and patients with low work instability (AS-WIS score < 11) were compared with those with moderate to high instability, through backward logistic regression.
Results. In all, 156 patients were assessed: mean (s.d.) age 41 (11) years, mean disease duration 15 (11) years; 71 (45.5%) were on TNF blockers. The mean AS-WIS score was 9.5 (5.5); 55 (35%) patients had moderate and 8 (5%) patients had high work instability. Correlations of the AS-WIS score with SpA scores were significant but moderate (BASDAI R = 0.42, BASFI R = 0.41, patient's global assessment R = 0.53; P < 0.0001). In multivariate analysis, high patient's global assessment was the only element associated with moderate to high work instability; demographic characteristics and treatments were not significant elements.
Conclusion. Work instability was found to be high and its main determinant was patient's global assessment. The predictive validity of the AS-WIS in terms of job retention should be further assessed.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>22087013</pmid><doi>10.1093/rheumatology/ker319</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Cohort Studies Cross-Sectional Studies Disability Evaluation Employment - statistics & numerical data Female Humans Male Middle Aged Reproducibility of Results Sickness Impact Profile Spondylitis, Ankylosing - diagnosis Spondylitis, Ankylosing - physiopathology |
title | Assessment of work instability in spondyloarthritis: a cross-sectional study using the ankylosing spondylitis work instability scale |
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