Adult hippocampal glucocorticoid receptor expression and dentate synaptic plasticity correlate with maternal care received by individuals early in life

Maternal care in mammals is the prevailing environmental influence during perinatal development. The adult rat offspring of mothers exhibiting increased levels of pup licking/grooming (LG; High LG mothers), compared to those reared by Low LG dams, show increased hippocampal glucocorticoid receptor e...

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Veröffentlicht in:	Hippocampus 2012-02, Vol.22 (2), p.255-266
Hauptverfasser:	van Hasselt, Felisa N., Cornelisse, Sandra, Yuan Zhang, Tie, Meaney, Michael J., Velzing, Els H., Krugers, Harm J., Joëls, Marian
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals dentate gyrus early-life environment Female Hippocampus - cytology Hippocampus - physiology Immunohistochemistry long-term potentiation Male Maternal Behavior morphology Neurogenesis - physiology Neuronal Plasticity - physiology programming Rats Rats, Long-Evans Real-Time Polymerase Chain Reaction Receptors, Glucocorticoid - biosynthesis Synaptic Transmission - physiology
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