Nicotinamide inhibits nuclear factor-kappa B translocation after transient focal cerebral ischemia

OBJECTIVE:We explored the putative anti-inflammatory effects of nicotinamide against experimental stroke. DESIGN:Prospective laboratory study. SETTING:Research laboratory in a university teaching hospital. SUBJECTS:Adult male Sprague-Dawley rats (250–300 g). INTERVENTIONS:The antioxidant, radical sc...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Critical care medicine 2012-02, Vol.40 (2), p.532-537
Hauptverfasser:	Chen, Tsung-Ying, Lin, Miao-Hui Sylvia, Lee, Wei-Ting, Huang, Sheng-Yang, Chen, Ying-Hsin, Lee, Ai-Chiang, Lin, Hsiao-Wen, Lee, E-Jian
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Behavior, Animal Biological and medical sciences Confidence Intervals Disease Models, Animal Electrophoresis, Gel, Two-Dimensional Immunoblotting Immunohistochemistry Intensive care medicine Interleukin-6 - analysis Interleukin-6 - metabolism Ischemic Attack, Transient - drug therapy Ischemic Attack, Transient - metabolism Ischemic Attack, Transient - pathology Lipid Peroxidation - physiology Male Medical sciences Neuropharmacology Neuroprotective agent NF-kappa B - drug effects NF-kappa B - metabolism Niacinamide - pharmacology Peroxidase - analysis Peroxidase - metabolism Pharmacology. Drug treatments Random Allocation Rats Rats, Sprague-Dawley Reference Values Statistics, Nonparametric Tumor Necrosis Factor-alpha - analysis Tumor Necrosis Factor-alpha - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!