The nasopharynx in infants with cleft lip and palate

Abstract Objective The purpose of this study was to use three-dimensional computed tomography data and computer imaging technology to assess the skeletal components of the naso-pharyngeal area in patients with cleft lip and palate and to quantify anatomical variations. Methods CT scans were obtained...

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Veröffentlicht in:International journal of pediatric otorhinolaryngology 2012-02, Vol.76 (2), p.227-234
Hauptverfasser: Rajion, Zainul A, Al-Khatib, Ali R, Netherway, David J, Townsend, Grant C, Anderson, Peter J, McLean, Neil R, Samsudin, Ab Rani
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container_end_page 234
container_issue 2
container_start_page 227
container_title International journal of pediatric otorhinolaryngology
container_volume 76
creator Rajion, Zainul A
Al-Khatib, Ali R
Netherway, David J
Townsend, Grant C
Anderson, Peter J
McLean, Neil R
Samsudin, Ab Rani
description Abstract Objective The purpose of this study was to use three-dimensional computed tomography data and computer imaging technology to assess the skeletal components of the naso-pharyngeal area in patients with cleft lip and palate and to quantify anatomical variations. Methods CT scans were obtained from 29 patients of Malay origin with cleft lip and palate aged between 0 and 12 months and 12 noncleft patients in the same age group, using a GE Lightspeed Plus Scanner housed in Hospital Universiti Sains Malaysia. Measurements were obtained using the ‘Persona’ three-dimensional software package, developed at Australian Craniofacial Unit, Adelaide. Results The results of the present study show that there is an increased nasopharyngeal space in cleft lip and palate that may lead to compression of the nasopharyngeal structures, including the Eustachian tube. Alterations of the medial pterygoid plate and the hamulus may lead to an alteration in the origin and orientation of the tensor veli palatini muscle leading to alteration in its function. Conclusions These anatomical variations may compromise the dilatory mechanism of the Eustachian tube, thus leading to recurrent middle ear infections in cleft children and subsequent loss of hearing.
doi_str_mv 10.1016/j.ijporl.2011.11.008
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Methods CT scans were obtained from 29 patients of Malay origin with cleft lip and palate aged between 0 and 12 months and 12 noncleft patients in the same age group, using a GE Lightspeed Plus Scanner housed in Hospital Universiti Sains Malaysia. Measurements were obtained using the ‘Persona’ three-dimensional software package, developed at Australian Craniofacial Unit, Adelaide. Results The results of the present study show that there is an increased nasopharyngeal space in cleft lip and palate that may lead to compression of the nasopharyngeal structures, including the Eustachian tube. Alterations of the medial pterygoid plate and the hamulus may lead to an alteration in the origin and orientation of the tensor veli palatini muscle leading to alteration in its function. Conclusions These anatomical variations may compromise the dilatory mechanism of the Eustachian tube, thus leading to recurrent middle ear infections in cleft children and subsequent loss of hearing.</description><identifier>ISSN: 0165-5876</identifier><identifier>EISSN: 1872-8464</identifier><identifier>DOI: 10.1016/j.ijporl.2011.11.008</identifier><identifier>PMID: 22136741</identifier><language>eng</language><publisher>Ireland: Elsevier Ireland Ltd</publisher><subject>Case-Control Studies ; Cleft Lip - diagnostic imaging ; Cleft Lip - physiopathology ; Cleft lip and palate ; Cleft Palate - diagnostic imaging ; Cleft Palate - physiopathology ; Computed tomography ; Female ; Humans ; Imaging, Three-Dimensional ; Infant ; Infant, Newborn ; Malaysia ; Male ; Nasopharynx ; Nasopharynx - anatomy &amp; histology ; Nasopharynx - diagnostic imaging ; Otolaryngology ; Pediatrics ; Reference Values ; Tomography, X-Ray Computed - methods</subject><ispartof>International journal of pediatric otorhinolaryngology, 2012-02, Vol.76 (2), p.227-234</ispartof><rights>Elsevier Ireland Ltd</rights><rights>2011 Elsevier Ireland Ltd</rights><rights>Copyright © 2011 Elsevier Ireland Ltd. 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Methods CT scans were obtained from 29 patients of Malay origin with cleft lip and palate aged between 0 and 12 months and 12 noncleft patients in the same age group, using a GE Lightspeed Plus Scanner housed in Hospital Universiti Sains Malaysia. Measurements were obtained using the ‘Persona’ three-dimensional software package, developed at Australian Craniofacial Unit, Adelaide. Results The results of the present study show that there is an increased nasopharyngeal space in cleft lip and palate that may lead to compression of the nasopharyngeal structures, including the Eustachian tube. Alterations of the medial pterygoid plate and the hamulus may lead to an alteration in the origin and orientation of the tensor veli palatini muscle leading to alteration in its function. Conclusions These anatomical variations may compromise the dilatory mechanism of the Eustachian tube, thus leading to recurrent middle ear infections in cleft children and subsequent loss of hearing.</description><subject>Case-Control Studies</subject><subject>Cleft Lip - diagnostic imaging</subject><subject>Cleft Lip - physiopathology</subject><subject>Cleft lip and palate</subject><subject>Cleft Palate - diagnostic imaging</subject><subject>Cleft Palate - physiopathology</subject><subject>Computed tomography</subject><subject>Female</subject><subject>Humans</subject><subject>Imaging, Three-Dimensional</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Malaysia</subject><subject>Male</subject><subject>Nasopharynx</subject><subject>Nasopharynx - anatomy &amp; histology</subject><subject>Nasopharynx - diagnostic imaging</subject><subject>Otolaryngology</subject><subject>Pediatrics</subject><subject>Reference Values</subject><subject>Tomography, X-Ray Computed - methods</subject><issn>0165-5876</issn><issn>1872-8464</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU1r3DAQhkVpaDZp_0EpvvXkjUaWZPkSKCFfEOihyVnI8oiVq5Vdydsk_z5aNumhl8ALc3lmhnmGkK9A10BBno1rP85TCmtGAdYllKoPZAWqZbXikn8kq4KJWqhWHpOTnEdKoaVCfCLHjEEjWw4rwu83WEWTp3lj0nN8qnwscSYuuXr0y6ayAd1SBT9XJg7VbIJZ8DM5ciZk_PJaT8nD1eX9xU199_P69uLHXW05yKV2TvaNUU0neAOdUYhMcOE61_c4sE4xLtTQ0F4pgR21zKJyvJU9StqIvofmlHw_zJ3T9GeHedFbny2GYCJOu6w7kLJTlHaF5AfSpinnhE7PyW_LRRqo3uvSoz7o0ntduqToKm3fXhfs-i0O_5re_BTg_ABgOfOvx6Sz9RgtDj6hXfQw-fc2_D_ABh-9NeE3PmMep12KRaEGnZmm-tf-ZfuPAVAqWuDNC4O-kTc</recordid><startdate>20120201</startdate><enddate>20120201</enddate><creator>Rajion, Zainul A</creator><creator>Al-Khatib, Ali R</creator><creator>Netherway, David J</creator><creator>Townsend, Grant C</creator><creator>Anderson, Peter J</creator><creator>McLean, Neil R</creator><creator>Samsudin, Ab Rani</creator><general>Elsevier Ireland Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20120201</creationdate><title>The nasopharynx in infants with cleft lip and palate</title><author>Rajion, Zainul A ; Al-Khatib, Ali R ; Netherway, David J ; Townsend, Grant C ; Anderson, Peter J ; McLean, Neil R ; Samsudin, Ab Rani</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c416t-ff6b3a83954319a8ee2545f9fbbed2982458d30b885e90c2ce8f476be6035bb13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Case-Control Studies</topic><topic>Cleft Lip - diagnostic imaging</topic><topic>Cleft Lip - physiopathology</topic><topic>Cleft lip and palate</topic><topic>Cleft Palate - diagnostic imaging</topic><topic>Cleft Palate - physiopathology</topic><topic>Computed tomography</topic><topic>Female</topic><topic>Humans</topic><topic>Imaging, Three-Dimensional</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Malaysia</topic><topic>Male</topic><topic>Nasopharynx</topic><topic>Nasopharynx - anatomy &amp; histology</topic><topic>Nasopharynx - diagnostic imaging</topic><topic>Otolaryngology</topic><topic>Pediatrics</topic><topic>Reference Values</topic><topic>Tomography, X-Ray Computed - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rajion, Zainul A</creatorcontrib><creatorcontrib>Al-Khatib, Ali R</creatorcontrib><creatorcontrib>Netherway, David J</creatorcontrib><creatorcontrib>Townsend, Grant C</creatorcontrib><creatorcontrib>Anderson, Peter J</creatorcontrib><creatorcontrib>McLean, Neil R</creatorcontrib><creatorcontrib>Samsudin, Ab Rani</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of pediatric otorhinolaryngology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rajion, Zainul A</au><au>Al-Khatib, Ali R</au><au>Netherway, David J</au><au>Townsend, Grant C</au><au>Anderson, Peter J</au><au>McLean, Neil R</au><au>Samsudin, Ab Rani</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The nasopharynx in infants with cleft lip and palate</atitle><jtitle>International journal of pediatric otorhinolaryngology</jtitle><addtitle>Int J Pediatr Otorhinolaryngol</addtitle><date>2012-02-01</date><risdate>2012</risdate><volume>76</volume><issue>2</issue><spage>227</spage><epage>234</epage><pages>227-234</pages><issn>0165-5876</issn><eissn>1872-8464</eissn><abstract>Abstract Objective The purpose of this study was to use three-dimensional computed tomography data and computer imaging technology to assess the skeletal components of the naso-pharyngeal area in patients with cleft lip and palate and to quantify anatomical variations. Methods CT scans were obtained from 29 patients of Malay origin with cleft lip and palate aged between 0 and 12 months and 12 noncleft patients in the same age group, using a GE Lightspeed Plus Scanner housed in Hospital Universiti Sains Malaysia. Measurements were obtained using the ‘Persona’ three-dimensional software package, developed at Australian Craniofacial Unit, Adelaide. Results The results of the present study show that there is an increased nasopharyngeal space in cleft lip and palate that may lead to compression of the nasopharyngeal structures, including the Eustachian tube. Alterations of the medial pterygoid plate and the hamulus may lead to an alteration in the origin and orientation of the tensor veli palatini muscle leading to alteration in its function. 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subjects Case-Control Studies
Cleft Lip - diagnostic imaging
Cleft Lip - physiopathology
Cleft lip and palate
Cleft Palate - diagnostic imaging
Cleft Palate - physiopathology
Computed tomography
Female
Humans
Imaging, Three-Dimensional
Infant
Infant, Newborn
Malaysia
Male
Nasopharynx
Nasopharynx - anatomy & histology
Nasopharynx - diagnostic imaging
Otolaryngology
Pediatrics
Reference Values
Tomography, X-Ray Computed - methods
title The nasopharynx in infants with cleft lip and palate
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