Synthesis, molecular docking study and antitumor activity of novel 2-phenylindole derivatives

The starting material, 4-(1-indol-2-yl)phenol 1 was obtained via Fischer synthesis. Vilsmeir Haack ’s formylation of 1 gave the carboxaldehyde derivative 2 which was subjected to different reactions affording the 3-substituted compounds 3– 10. Compound 1 reacted with halo esters to give 11 and 12a,...

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