The combined ratios of L-arginine and asymmetric and symmetric dimethylarginine as biomarkers in spontaneously hypertensive rats

Hypertension and hypertensive end-organ damage have been associated with decreased nitric oxide (NO) bioavailability. Asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) both can inhibit NO availability by competition with L-arginine (L-Arg). However, whether a combined analysis...

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Veröffentlicht in:	Translational research : the journal of laboratory and clinical medicine 2012-02, Vol.159 (2), p.90-98
Hauptverfasser:	Hsu, Chien-Ning, Huang, Li-Tung, Lau, Ying-Tung, Lin, Ching-Yuang, Tain, You-Lin
Format:	Artikel
Sprache:	eng
Schlagworte:	Amidohydrolases - analysis Amidohydrolases - metabolism Animals Arginine - analogs & derivatives Arginine - blood Arginine - metabolism Arginine - urine Biomarkers - metabolism Blood Pressure Hypertension - blood Hypertension - physiopathology Internal Medicine Male Models, Animal Nitric Oxide - deficiency Nitric Oxide - urine Rats Rats, Inbred SHR - metabolism Rats, Inbred WKY
Online-Zugang:	Volltext
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