Role of c-MYC in alternative activation of human macrophages and tumor-associated macrophage biology

In response to microenvironmental signals, macrophages undergo different activation, including the “classic” proinflammatory phenotype (also called M1), the “alternative” activation induced by the IL-4/IL-13 trigger, and the related but distinct heterogeneous M2 polarization associated with the anti...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Blood 2012-01, Vol.119 (2), p.411-421
Hauptverfasser:	Pello, Oscar M., De Pizzol, Maria, Mirolo, Massimiliano, Soucek, Laura, Zammataro, Luca, Amabile, Angelo, Doni, Andrea, Nebuloni, Manuela, Swigart, Lamorna B., Evan, Gerard I., Mantovani, Alberto, Locati, Massimo
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Blotting, Western Breast Neoplasms - genetics Breast Neoplasms - metabolism Breast Neoplasms - pathology Cell Differentiation Cells, Cultured Chromatin Immunoprecipitation Colon - metabolism Colon - pathology Colonic Neoplasms - genetics Colonic Neoplasms - metabolism Colonic Neoplasms - pathology Female Gene Expression Profiling Gene Expression Regulation, Neoplastic Hematologic and hematopoietic diseases Humans Interleukin-4 - pharmacology Macrophage Activation - drug effects Macrophages - cytology Macrophages - metabolism Medical sciences Oligonucleotide Array Sequence Analysis Pancreatic Neoplasms - genetics Pancreatic Neoplasms - metabolism Pancreatic Neoplasms - pathology PPAR gamma - genetics PPAR gamma - metabolism Proto-Oncogene Proteins c-myc - genetics Proto-Oncogene Proteins c-myc - metabolism Real-Time Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics Signal Transduction STAT6 Transcription Factor - genetics STAT6 Transcription Factor - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!