Evaluation of the prognostic significance of BCL6 gene expression in canine high-grade B-cell lymphoma

The clinical usefulness of BCL6 gene expression was evaluated as a prognostic indicator in dogs with high-grade B-cell lymphoma. Forty-four dogs were diagnosed with centroblastic or B-cell immunoblastic type lymphoma according to the updated Kiel classification. BCL6 mRNA expression was measured by...

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Veröffentlicht in:	The veterinary journal (1997) 2012, Vol.191 (1), p.108-114
Hauptverfasser:	Sato, Masahiko, Kanemoto, Hideyuki, Kagawa, Yumiko, Kobayashi, Tetsuya, Goto-Koshino, Yuko, Mochizuki, Hiroyuki, Takahashi, Masashi, Fujino, Yasuhito, Ohno, Koichi, Tsujimoto, Hajime
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals B-lymphocytes BCL6 Diffuse large B-cell lymphoma Disease-Free Survival Dog Dog Diseases - genetics Dog Diseases - mortality Dog Diseases - pathology Dogs Female gene expression Gene Expression Regulation, Neoplastic Humans immunohistochemistry Lymphoma Lymphoma, B-Cell - genetics Lymphoma, B-Cell - mortality Lymphoma, B-Cell - veterinary Male messenger RNA Neoplasm Recurrence, Local - genetics Neoplasm Recurrence, Local - mortality Neoplasm Recurrence, Local - veterinary Neoplasm Staging Oncology Prognosis protein synthesis Proto-Oncogene Proteins c-bcl-6 - genetics quantitative polymerase chain reaction RNA, Messenger - analysis
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