Gold-mediated bifunctional modification of oligosaccharides via a three-component coupling reaction

An efficient modular approach for single-site incorporation of two independent functionalities (amines and alkynes) into aldehyde-containing oligosaccharides concurrently by using a one-pot gold-mediated three-component coupling reaction in aqueous medium under mild conditions has been developed.

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Veröffentlicht in:Organic & biomolecular chemistry 2012-02, Vol.10 (5), p.925-930
Hauptverfasser: Kung, Karen Ka-Yan, Li, Gai-Li, Zou, Lan, Chong, Hiu-Chi, Leung, Yun-Chung, Wong, Ka-Hing, Lo, Vanessa Kar-Yan, Che, Chi-Ming, Wong, Man-Kin
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container_issue 5
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container_title Organic & biomolecular chemistry
container_volume 10
creator Kung, Karen Ka-Yan
Li, Gai-Li
Zou, Lan
Chong, Hiu-Chi
Leung, Yun-Chung
Wong, Ka-Hing
Lo, Vanessa Kar-Yan
Che, Chi-Ming
Wong, Man-Kin
description An efficient modular approach for single-site incorporation of two independent functionalities (amines and alkynes) into aldehyde-containing oligosaccharides concurrently by using a one-pot gold-mediated three-component coupling reaction in aqueous medium under mild conditions has been developed.
doi_str_mv 10.1039/c1ob06429k
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source MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection
subjects Aldehydes - chemistry
Alkynes - chemistry
Amines - chemistry
Gold - chemistry
Oligosaccharides - chemistry
title Gold-mediated bifunctional modification of oligosaccharides via a three-component coupling reaction
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