Plasminogen deficiency attenuates postnatal erythropoiesis in male C57BL/6 mice through decreased activity of the LH-testosterone axis

Novel roles for the serine protease plasmin have been implicated recently in physiological and pathological processes. However, whether plasmin is involved in erythropoiesis is not known. In the present study, we studied the consequences of plasminogen deficiency on erythropoiesis in plasminogen-def...

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Veröffentlicht in:	Experimental hematology 2012-02, Vol.40 (2), p.143-154
Hauptverfasser:	Okaji, Yurai, Tashiro, Yoshihiko, Gritli, Ismael, Nishida, Chiemi, Sato, Aki, Ueno, Yoko, Del Canto Gonzalez, Sandra, Ohki-Koizumi, Makiko, Akiyama, Haruyo, Nakauchi, Hiromitsu, Hattori, Koichi, Heissig, Beate
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Animals Erythropoiesis Erythropoietin - blood Female Fibrinolysin - physiology Hematology, Oncology and Palliative Medicine Luteinizing Hormone - physiology Male Mice Mice, Inbred C57BL Mice, Knockout Plasminogen - deficiency Plasminogen - physiology Testosterone - physiology
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