Dosing of 3-Factor Prothrombin Complex Concentrate for International Normalized Ratio Reversal

BACKGROUND: Three-factor prothrombin complex concentrate (PCC) is commonly used for reversal of international normalized ratio (INR) in patients who are bleeding or require emergency surgery. However, there is little information regarding the optimal dosing strategy for achieving adequate INR revers...

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Veröffentlicht in:	The Annals of pharmacotherapy 2012-01, Vol.46 (1), p.51-56
Hauptverfasser:	Baggs, Jennifer H, Patanwala, Asad E, Williams, Evan M, Erstad, Brian L
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Biological and medical sciences Blood Coagulation Factors - administration & dosage Blood Coagulation Factors - therapeutic use Cohort Studies Dose-Response Relationship, Drug Female Hemorrhage - blood Hemorrhage - prevention & control Humans International Normalized Ratio Logistic Models Male Medical sciences Middle Aged Pharmacology. Drug treatments Retrospective Studies Treatment Outcome
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