Association of Baseline Anxiety With Depression Persistence at 6 Months in Patients With Acute Cardiac Illness
To assess the association of baseline anxiety with depression persistence and change in depressive symptoms 6 months after cardiac hospitalization. Data were analyzed from 137 depressed patients hospitalized on inpatient cardiac units for acute coronary syndrome, decompensated heart failure, or arrh...
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| Veröffentlicht in: | Psychosomatic medicine 2012-01, Vol.74 (1), p.93-99, Article 93 |
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| creator | Celano, Christopher M Mastromauro, Carol A Lenihan, Emma C Januzzi, James L Rollman, Bruce L Huffman, Jeff C |
| description | To assess the association of baseline anxiety with depression persistence and change in depressive symptoms 6 months after cardiac hospitalization.
Data were analyzed from 137 depressed patients hospitalized on inpatient cardiac units for acute coronary syndrome, decompensated heart failure, or arrhythmia and who were enrolled in a randomized trial of collaborative care depression management. Subjects' demographic, medical, and psychiatric information at baseline was compiled. Measures of health-related quality of life, cardiac symptoms, and psychiatric symptoms, including the Hospital Anxiety and Depression Scale-anxiety subscale (HADS-A) for anxiety, were obtained at baseline and serially during a 6-month follow-up period. The association between baseline HADS-A score and depression persistence ( |
| doi_str_mv | 10.1097/PSY.0b013e31823d38bc |
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Data were analyzed from 137 depressed patients hospitalized on inpatient cardiac units for acute coronary syndrome, decompensated heart failure, or arrhythmia and who were enrolled in a randomized trial of collaborative care depression management. Subjects' demographic, medical, and psychiatric information at baseline was compiled. Measures of health-related quality of life, cardiac symptoms, and psychiatric symptoms, including the Hospital Anxiety and Depression Scale-anxiety subscale (HADS-A) for anxiety, were obtained at baseline and serially during a 6-month follow-up period. The association between baseline HADS-A score and depression persistence (<50% reduction in depressive symptoms on the Patient Health Questionnaire-9) at 6 months was assessed by multivariate logistic regression accounting for the effects of multiple relevant medical and psychological covariates. The association between baseline HADS-A score and improvement in depressive symptoms (Patient Health Questionnaire-9) from baseline at 6 months was assessed by linear regression accounting for the same covariates.
Baseline HADS-A score was independently associated with depression persistence at 6 months (odds ratio = 1.11, 95% confidence interval = 1.01-1.22, p = .03). Likewise, higher baseline HADS-A score was associated with less improvement in depressive symptoms at 6 months (β = -0.34, p = .01).
Among a cohort of depressed cardiac patients, higher baseline anxiety score was linked with lesser improvement in depressive symptoms and increased likelihood of depression persistence at 6 months, independent of multiple relevant covariates.
clinicaltrials.gov Identifier: NCT00847132.</description><identifier>ISSN: 0033-3174</identifier><identifier>EISSN: 1534-7796</identifier><identifier>DOI: 10.1097/PSY.0b013e31823d38bc</identifier><identifier>PMID: 22210240</identifier><language>eng</language><publisher>United States</publisher><subject>Acute Disease ; Anxiety - epidemiology ; Anxiety - psychology ; Comorbidity ; Data Collection ; Depression - epidemiology ; Depression - psychology ; Depression - therapy ; Female ; Heart Diseases - epidemiology ; Heart Diseases - psychology ; Heart Diseases - therapy ; Hospitalization - statistics & numerical data ; Humans ; Male ; Middle Aged ; Patient Care Team ; Psychiatric Status Rating Scales - standards ; Quality of Life ; Regression Analysis ; Risk Factors ; Severity of Illness Index ; Time Factors ; Treatment Outcome</subject><ispartof>Psychosomatic medicine, 2012-01, Vol.74 (1), p.93-99, Article 93</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c1843-37997ac34ecbf88c87c193405edcf37e9d455dd7981ccc471721876cb64bf6d22</citedby></display><links><openurl>$$Topenurl_article</openurl><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22210240$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Celano, Christopher M</creatorcontrib><creatorcontrib>Mastromauro, Carol A</creatorcontrib><creatorcontrib>Lenihan, Emma C</creatorcontrib><creatorcontrib>Januzzi, James L</creatorcontrib><creatorcontrib>Rollman, Bruce L</creatorcontrib><creatorcontrib>Huffman, Jeff C</creatorcontrib><title>Association of Baseline Anxiety With Depression Persistence at 6 Months in Patients With Acute Cardiac Illness</title><title>Psychosomatic medicine</title><addtitle>Psychosom Med</addtitle><description>To assess the association of baseline anxiety with depression persistence and change in depressive symptoms 6 months after cardiac hospitalization.
Data were analyzed from 137 depressed patients hospitalized on inpatient cardiac units for acute coronary syndrome, decompensated heart failure, or arrhythmia and who were enrolled in a randomized trial of collaborative care depression management. Subjects' demographic, medical, and psychiatric information at baseline was compiled. Measures of health-related quality of life, cardiac symptoms, and psychiatric symptoms, including the Hospital Anxiety and Depression Scale-anxiety subscale (HADS-A) for anxiety, were obtained at baseline and serially during a 6-month follow-up period. The association between baseline HADS-A score and depression persistence (<50% reduction in depressive symptoms on the Patient Health Questionnaire-9) at 6 months was assessed by multivariate logistic regression accounting for the effects of multiple relevant medical and psychological covariates. The association between baseline HADS-A score and improvement in depressive symptoms (Patient Health Questionnaire-9) from baseline at 6 months was assessed by linear regression accounting for the same covariates.
Baseline HADS-A score was independently associated with depression persistence at 6 months (odds ratio = 1.11, 95% confidence interval = 1.01-1.22, p = .03). Likewise, higher baseline HADS-A score was associated with less improvement in depressive symptoms at 6 months (β = -0.34, p = .01).
Among a cohort of depressed cardiac patients, higher baseline anxiety score was linked with lesser improvement in depressive symptoms and increased likelihood of depression persistence at 6 months, independent of multiple relevant covariates.
clinicaltrials.gov Identifier: NCT00847132.</description><subject>Acute Disease</subject><subject>Anxiety - epidemiology</subject><subject>Anxiety - psychology</subject><subject>Comorbidity</subject><subject>Data Collection</subject><subject>Depression - epidemiology</subject><subject>Depression - psychology</subject><subject>Depression - therapy</subject><subject>Female</subject><subject>Heart Diseases - epidemiology</subject><subject>Heart Diseases - psychology</subject><subject>Heart Diseases - therapy</subject><subject>Hospitalization - statistics & numerical data</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Patient Care Team</subject><subject>Psychiatric Status Rating Scales - standards</subject><subject>Quality of Life</subject><subject>Regression Analysis</subject><subject>Risk Factors</subject><subject>Severity of Illness Index</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><issn>0033-3174</issn><issn>1534-7796</issn><fulltext>false</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtuFDEQRa0IlAwJf4CQd6wm-NVtO7thwiNSEJECili13NXViqMe9-DySOTvcTKBRRasalH3niodxt5IcSqFt--vrn-eil5IjVo6pQftejhgC9los7TWty_YQgitl1pac8ReEd0JIYzX6pAdKaWkUEYsWFoRzRBDiXPi88g_BMIpJuSr9Dtiuec3sdzyc9xmJHrIXGGmSAUTIA-Ft_zrnMot8VhXlYKp0L6zgl1Bvg55iAH4xTSlSjhhL8cwEb5-msfsx6eP39dflpffPl-sV5dLkM7Un633NoA2CP3oHDgL0msjGhxg1Bb9YJpmGKx3EgCMlVZJZ1voW9OP7aDUMXu3527z_GuHVLpNJMBpCgnnHXW-anLCqKYmzT4JeSbKOHbbHDch33dSdA-iuyq6ey661t4-Hdj1Gxz-lf6arYGzZ1yI5VFzySFO_6f_AZrVji8</recordid><startdate>201201</startdate><enddate>201201</enddate><creator>Celano, Christopher M</creator><creator>Mastromauro, Carol A</creator><creator>Lenihan, Emma C</creator><creator>Januzzi, James L</creator><creator>Rollman, Bruce L</creator><creator>Huffman, Jeff C</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201201</creationdate><title>Association of Baseline Anxiety With Depression Persistence at 6 Months in Patients With Acute Cardiac Illness</title><author>Celano, Christopher M ; Mastromauro, Carol A ; Lenihan, Emma C ; Januzzi, James L ; Rollman, Bruce L ; Huffman, Jeff C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1843-37997ac34ecbf88c87c193405edcf37e9d455dd7981ccc471721876cb64bf6d22</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Acute Disease</topic><topic>Anxiety - epidemiology</topic><topic>Anxiety - psychology</topic><topic>Comorbidity</topic><topic>Data Collection</topic><topic>Depression - epidemiology</topic><topic>Depression - psychology</topic><topic>Depression - therapy</topic><topic>Female</topic><topic>Heart Diseases - epidemiology</topic><topic>Heart Diseases - psychology</topic><topic>Heart Diseases - therapy</topic><topic>Hospitalization - statistics & numerical data</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Patient Care Team</topic><topic>Psychiatric Status Rating Scales - standards</topic><topic>Quality of Life</topic><topic>Regression Analysis</topic><topic>Risk Factors</topic><topic>Severity of Illness Index</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><creatorcontrib>Celano, Christopher M</creatorcontrib><creatorcontrib>Mastromauro, Carol A</creatorcontrib><creatorcontrib>Lenihan, Emma C</creatorcontrib><creatorcontrib>Januzzi, James L</creatorcontrib><creatorcontrib>Rollman, Bruce L</creatorcontrib><creatorcontrib>Huffman, Jeff C</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Psychosomatic medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>no_fulltext</fulltext></delivery><addata><au>Celano, Christopher M</au><au>Mastromauro, Carol A</au><au>Lenihan, Emma C</au><au>Januzzi, James L</au><au>Rollman, Bruce L</au><au>Huffman, Jeff C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Association of Baseline Anxiety With Depression Persistence at 6 Months in Patients With Acute Cardiac Illness</atitle><jtitle>Psychosomatic medicine</jtitle><addtitle>Psychosom Med</addtitle><date>2012-01</date><risdate>2012</risdate><volume>74</volume><issue>1</issue><spage>93</spage><epage>99</epage><pages>93-99</pages><artnum>93</artnum><issn>0033-3174</issn><eissn>1534-7796</eissn><abstract>To assess the association of baseline anxiety with depression persistence and change in depressive symptoms 6 months after cardiac hospitalization.
Data were analyzed from 137 depressed patients hospitalized on inpatient cardiac units for acute coronary syndrome, decompensated heart failure, or arrhythmia and who were enrolled in a randomized trial of collaborative care depression management. Subjects' demographic, medical, and psychiatric information at baseline was compiled. Measures of health-related quality of life, cardiac symptoms, and psychiatric symptoms, including the Hospital Anxiety and Depression Scale-anxiety subscale (HADS-A) for anxiety, were obtained at baseline and serially during a 6-month follow-up period. The association between baseline HADS-A score and depression persistence (<50% reduction in depressive symptoms on the Patient Health Questionnaire-9) at 6 months was assessed by multivariate logistic regression accounting for the effects of multiple relevant medical and psychological covariates. The association between baseline HADS-A score and improvement in depressive symptoms (Patient Health Questionnaire-9) from baseline at 6 months was assessed by linear regression accounting for the same covariates.
Baseline HADS-A score was independently associated with depression persistence at 6 months (odds ratio = 1.11, 95% confidence interval = 1.01-1.22, p = .03). Likewise, higher baseline HADS-A score was associated with less improvement in depressive symptoms at 6 months (β = -0.34, p = .01).
Among a cohort of depressed cardiac patients, higher baseline anxiety score was linked with lesser improvement in depressive symptoms and increased likelihood of depression persistence at 6 months, independent of multiple relevant covariates.
clinicaltrials.gov Identifier: NCT00847132.</abstract><cop>United States</cop><pmid>22210240</pmid><doi>10.1097/PSY.0b013e31823d38bc</doi><tpages>7</tpages></addata></record> |
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| subjects | Acute Disease Anxiety - epidemiology Anxiety - psychology Comorbidity Data Collection Depression - epidemiology Depression - psychology Depression - therapy Female Heart Diseases - epidemiology Heart Diseases - psychology Heart Diseases - therapy Hospitalization - statistics & numerical data Humans Male Middle Aged Patient Care Team Psychiatric Status Rating Scales - standards Quality of Life Regression Analysis Risk Factors Severity of Illness Index Time Factors Treatment Outcome |
| title | Association of Baseline Anxiety With Depression Persistence at 6 Months in Patients With Acute Cardiac Illness |
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