Three-dimensional imaging of the unsectioned adult spinal cord to assess axon regeneration and glial responses after injury

Ali Ertürk and colleagues present a novel tetrahydrofuran-based histological tissue clearing procedure that renders fixed and unsectioned adult CNS tissue (spinal cord and brainstem) transparent and, as such, fully amenable to a range of different optical imaging techniques. This three-dimensional i...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature (London) 2012-01, Vol.18 (1), p.166-171
Hauptverfasser:	Ertürk, Ali, Mauch, Christoph P, Hellal, Farida, Förstner, Friedrich, Keck, Tara, Becker, Klaus, Jährling, Nina, Steffens, Heinz, Richter, Melanie, Hübener, Mark, Kramer, Edgar, Kirchhoff, Frank, Dodt, Hans Ulrich, Bradke, Frank
Format:	Artikel
Sprache:	eng
Schlagworte:	631/378/1687 631/378/2596 692/699/578 692/700/1421/2025 Animals Axons Axons - physiology Axons - ultrastructure Biomedical and Life Sciences Biomedicine Cancer Research Central nervous system Development and progression Diagnosis Experiments Fluorescence Furans - chemistry Imaging, Three-Dimensional - methods Infectious Diseases Lesions Metabolic Diseases Methods Mice Microglia - physiology Microglia - ultrastructure Microscopy Microscopy, Confocal - methods Molecular Medicine Nervous system Neuroglia Neurons Neurosciences Pathology Physiological aspects Spinal cord Spinal cord injuries Spinal Cord Injuries - physiopathology Spinal Cord Regeneration technical-report Three dimensional imaging
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!