Patient-focused endpoints in advanced cancer: Criterion-based validation of accelerometer-based activity monitoring

Summary Background & aims Objective assessment of daily physical activity (PA) by body-worn accelerometers offers potential as a novel endpoint in the clinical management of advanced cancer patients. This study aimed to assess criterion-based validity of an accelerometer-based activity monitorin...

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Veröffentlicht in:	Clinical nutrition (Edinburgh, Scotland) Scotland), 2011-12, Vol.30 (6), p.812-821
Hauptverfasser:	Skipworth, Richard J.E, Stene, Guro B, Dahele, Max, Hendry, Paul O, Small, Alexandra C, Blum, David, Kaasa, Stein, Trottenberg, Peter, Radbruch, Lukas, Strasser, Florian, Preston, Tom, Fearon, Kenneth C.H, Helbostad, Jorunn L
Format:	Artikel
Sprache:	eng
Schlagworte:	Accelerometer-based activity monitoring Adult Aged Aged, 80 and over Biological and medical sciences Calorimetry, Indirect Cancer Criterion-based validity Energy expenditure Energy Metabolism - physiology Feeding. Feeding behavior Female Fundamental and applied biological sciences. Psychology Gastroenterology and Hepatology Humans Male Middle Aged Monitoring, Physiologic - methods Motor Activity - physiology Neoplasms - metabolism Neoplasms - physiopathology Physical activity Pilot Projects Reproducibility of Results Vertebrates: anatomy and physiology, studies on body, several organs or systems
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Zusammenfassung:	Summary Background & aims Objective assessment of daily physical activity (PA) by body-worn accelerometers offers potential as a novel endpoint in the clinical management of advanced cancer patients. This study aimed to assess criterion-based validity of an accelerometer-based activity monitoring system (AM-system), ActivPAL™, using two different methods. Methods Advanced cancer in patients and outpatients (Karnofsky Performance Status (KPS) 40–100). ActivPAL™ measurements were validated against (i) observations and (ii) energy expenditure (EE) measured by 2-week doubly-labelled water (DLW) protocol. Results Absolute errors for mean time spent in different body positions (
ISSN:	0261-5614 1532-1983
DOI:	10.1016/j.clnu.2011.05.010