A simple and fast liquid chromatography–tandem mass spectrometry method for measurement of underivatized l-arginine, symmetric dimethylarginine, and asymmetric dimethylarginine and establishment of the reference ranges

Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthase and an established biomarker for endothelial function, while symmetric dimethylarginine (SDMA), an emerging biomarker for renal function, has been shown to outperform creatinine-based equations for estimated glome...

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Veröffentlicht in:	Analytical and bioanalytical chemistry 2012-01, Vol.402 (2), p.771-779
Hauptverfasser:	El-Khoury, Joe M., Bunch, Dustin R., Reineks, Edmunds, Jackson, Raymond, Steinle, Roxanne, Wang, Sihe
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analysis Analytical Chemistry Arginine Arginine - analogs & derivatives Arginine - blood Asymmetry Biochemistry Biomarkers Characterization and Evaluation of Materials Chemistry Chemistry and Materials Science Chromatography Chromatography, High Pressure Liquid - standards Clinical Laboratory Techniques - standards Female Filtration Food Science Formic acid Humans Inhibitors Laboratory Medicine Liquid chromatography Liquids Male Mass spectrometry Mathematical analysis Measurement Methods Methyl alcohol Middle Aged Monitoring/Environmental Analysis Nitric oxide Nitriles Original Paper Precipitation (Meteorology) Reference Values Tandem Mass Spectrometry - standards Young Adult
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