Subchondral bone as a key target for osteoarthritis treatment

Osteoarthritis treatment should contemplate the improvement of subchondral bone quality. This therapeutic approach must be individualized in each patient depending on the BMD status and the physiopathological subgroup of osteoarthitis (OA). BMD: bone mineral density; SB: subchondral bone. Osteoarthr...

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Veröffentlicht in:	Biochemical pharmacology 2012-02, Vol.83 (3), p.315-323
Hauptverfasser:	Castañeda, Santos, Roman-Blas, Jorge A., Largo, Raquel, Herrero-Beaumont, Gabriel
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antiresorptives Bone (subchondral) bone density Bone mass bone metabolism Bone Remodeling - drug effects Bone Remodeling - physiology Bone turnover cartilage Cartilage diseases Cartilage, Articular - drug effects Cartilage, Articular - metabolism Cartilage, Articular - pathology Clinical Trials as Topic - methods Drug Delivery Systems - methods Drugs elderly Evolution Geriatrics Humans Joint diseases New therapies Osteoarthritis Osteoarthritis - drug therapy Osteoarthritis - metabolism Osteoarthritis - pathology Osteoporosis Pathogenesis patients Quality of life Reviews Subchondral bone Treatment Outcome
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