Changes in thymic regulatory T-cell maturation from birth to puberty: Differences in atopic children

Background Characterization of regulatory immune pathways is a research priority for both the pathogenesis of allergic disease and potential therapeutic strategies. Objective The thymus is a rich source of regulatory T (Treg) cells, which offers a novel opportunity to document the maturation of thes...

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Veröffentlicht in:	Journal of allergy and clinical immunology 2012-01, Vol.129 (1), p.199-206.e4
Hauptverfasser:	Tulic, Meri K., BSc, PhD, Andrews, David, MD, Crook, Maxine L., BSc, Charles, Adrian, MD, Tourigny, Michelle R., PhD, Moqbel, Redwan, PhD, FRCPath, Prescott, Susan L., MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Age Age Factors Allergies allergy Allergy and Immunology atopy Autoimmune diseases Biological and medical sciences Cell culture Child Child, Preschool children Cytokines - metabolism Disease Female Food Food allergies Fundamental and applied biological sciences. Psychology Fundamental immunology Hospitals Humans Hypersensitivity, Immediate - immunology Hypersensitivity, Immediate - metabolism immune maturation Immunopathology Infant Infant, Newborn Lymphocytes Male Medical sciences Questionnaires Regulatory T cells Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis sensitization Skin Surgery T-Lymphocytes, Regulatory - immunology T-Lymphocytes, Regulatory - metabolism Th2 Cells - immunology thymus Thymus Gland - growth & development Thymus Gland - immunology Thymus Gland - pathology
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