Long-term neurological outcome of term-born children treated with two or more anti-epileptic drugs during the neonatal period

Abstract Background Neonatal seizures may persist despite treatment with multiple anti-epileptic drugs (AEDs). Objective To determine in term-born infants with seizures that required two or more AEDs, whether treatment efficacy and/or the underlying disorder were related to neurological outcome. Des...

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Veröffentlicht in:	Early human development 2012-01, Vol.88 (1), p.33-38
Hauptverfasser:	van der Heide, Mariska J, Roze, Elise, van der Veere, Christa N, ter Horst, Hendrik J, Brouwer, Oebele F, Bos, Arend F
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Anti-epileptic drugs Anticonvulsants - administration & dosage Anticonvulsants - therapeutic use Apgar Score Biological and medical sciences Child Child, Preschool Children Convulsions Drugs Electroencephalography - methods Embryology: invertebrates and vertebrates. Teratology Epilepsy Epilepsy - diagnosis Epilepsy - drug therapy Epilepsy - etiology Female Follow-up Follow-Up Studies Fundamental and applied biological sciences. Psychology Humans Infant Infant, Newborn Infants Intensive Care Units, Neonatal Lidocaine - administration & dosage Lidocaine - therapeutic use Logistic Models Male Midazolam - administration & dosage Midazolam - therapeutic use Mortality Neonatal and Perinatal Medicine Neonatal seizures Neonates Neurological dysfunction Paralysis Phenobarbital - administration & dosage Phenobarbital - therapeutic use Prognosis Risk Factors Seizure control Seizures Treatment Outcome
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