Long-term Survival Following Resection of Brain Metastases from Pancreatic Cancer
Brain metastases originating from pancreatic cancer are associated with a dismal prognosis and, generally, therapeutic options remain palliative. We present the cases of two patients that developed brain metastases after resection of a pancreatic ductal adenocarcinoma. Brain metastases were resected...
Gespeichert in:
Veröffentlicht in: | Anticancer research 2011-12, Vol.31 (12), p.4599-4603 |
---|---|
Hauptverfasser: | , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 4603 |
---|---|
container_issue | 12 |
container_start_page | 4599 |
container_title | Anticancer research |
container_volume | 31 |
creator | LEMKE, Johannes BARTH, Thomas F. E JUCHEMS, Markus KAPAPA, Thomas HENNE-BRUNS, Doris KORNMANN, Marko |
description | Brain metastases originating from pancreatic cancer are associated with a dismal prognosis and, generally, therapeutic options remain palliative. We present the cases of two patients that developed brain metastases after resection of a pancreatic ductal adenocarcinoma. Brain metastases were resected successfully and neither patients developed any further tumor recurrence. These cases demonstrate that resection of brain metastatic lesions originating from pancreatic ductal adenocarcinoma is a reasonable therapeutic option with a chance for complete cure in some cases. |
format | Article |
fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_912795491</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>912795491</sourcerecordid><originalsourceid>FETCH-LOGICAL-p240t-7721be992e665242f62de611d9a2b29dc527fc4fd07c98952076d42c9f1d50d83</originalsourceid><addsrcrecordid>eNpF0E1LAzEQBuAgiq3VvyC5iKeFfGyS5qjFqlDx-7ykyaREspua7Fb89y5YEQbmPTwMvHOAplRpWinBySGaEiZIpQgRE3RSygchUuo5P0YTxqjWnMspel6lblP1kFv8OuRd2JmIlynG9BW6DX6BArYPqcPJ4-tsQocfoDdlHCjY59TiJ9PZDKYPFi_GCPkUHXkTC5zt9wy9L2_eFnfV6vH2fnG1qrasJn2lFKNr0JqBlILVzEvmQFLqtGFrpp0VTHlbe0eU1XMtGFHS1cxqT50gbs5n6PL37janzwFK37ShWIjRdJCG0mjKlBa1pqM838th3YJrtjm0Jn83f18YwcUemGJN9HksEsq_E5xTQgn_AV9DZfA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>912795491</pqid></control><display><type>article</type><title>Long-term Survival Following Resection of Brain Metastases from Pancreatic Cancer</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>LEMKE, Johannes ; BARTH, Thomas F. E ; JUCHEMS, Markus ; KAPAPA, Thomas ; HENNE-BRUNS, Doris ; KORNMANN, Marko</creator><creatorcontrib>LEMKE, Johannes ; BARTH, Thomas F. E ; JUCHEMS, Markus ; KAPAPA, Thomas ; HENNE-BRUNS, Doris ; KORNMANN, Marko</creatorcontrib><description>Brain metastases originating from pancreatic cancer are associated with a dismal prognosis and, generally, therapeutic options remain palliative. We present the cases of two patients that developed brain metastases after resection of a pancreatic ductal adenocarcinoma. Brain metastases were resected successfully and neither patients developed any further tumor recurrence. These cases demonstrate that resection of brain metastatic lesions originating from pancreatic ductal adenocarcinoma is a reasonable therapeutic option with a chance for complete cure in some cases.</description><identifier>ISSN: 0250-7005</identifier><identifier>EISSN: 1791-7530</identifier><identifier>PMID: 22199336</identifier><language>eng</language><publisher>Attiki: International Institute of Anticancer Research</publisher><subject>Aged ; Biological and medical sciences ; Brain Neoplasms - mortality ; Brain Neoplasms - secondary ; Carcinoma, Pancreatic Ductal - mortality ; Carcinoma, Pancreatic Ductal - pathology ; Carcinoma, Pancreatic Ductal - surgery ; Female ; Humans ; Male ; Medical sciences ; Middle Aged ; Neoplasm Metastasis ; Neurology ; Pancreatic Neoplasms - mortality ; Pancreatic Neoplasms - pathology ; Pancreatic Neoplasms - surgery ; Prognosis ; Recurrence ; Time Factors ; Tomography, X-Ray Computed - methods ; Tumors ; Tumors of the nervous system. Phacomatoses</subject><ispartof>Anticancer research, 2011-12, Vol.31 (12), p.4599-4603</ispartof><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=25331010$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22199336$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>LEMKE, Johannes</creatorcontrib><creatorcontrib>BARTH, Thomas F. E</creatorcontrib><creatorcontrib>JUCHEMS, Markus</creatorcontrib><creatorcontrib>KAPAPA, Thomas</creatorcontrib><creatorcontrib>HENNE-BRUNS, Doris</creatorcontrib><creatorcontrib>KORNMANN, Marko</creatorcontrib><title>Long-term Survival Following Resection of Brain Metastases from Pancreatic Cancer</title><title>Anticancer research</title><addtitle>Anticancer Res</addtitle><description>Brain metastases originating from pancreatic cancer are associated with a dismal prognosis and, generally, therapeutic options remain palliative. We present the cases of two patients that developed brain metastases after resection of a pancreatic ductal adenocarcinoma. Brain metastases were resected successfully and neither patients developed any further tumor recurrence. These cases demonstrate that resection of brain metastatic lesions originating from pancreatic ductal adenocarcinoma is a reasonable therapeutic option with a chance for complete cure in some cases.</description><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Brain Neoplasms - mortality</subject><subject>Brain Neoplasms - secondary</subject><subject>Carcinoma, Pancreatic Ductal - mortality</subject><subject>Carcinoma, Pancreatic Ductal - pathology</subject><subject>Carcinoma, Pancreatic Ductal - surgery</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Neoplasm Metastasis</subject><subject>Neurology</subject><subject>Pancreatic Neoplasms - mortality</subject><subject>Pancreatic Neoplasms - pathology</subject><subject>Pancreatic Neoplasms - surgery</subject><subject>Prognosis</subject><subject>Recurrence</subject><subject>Time Factors</subject><subject>Tomography, X-Ray Computed - methods</subject><subject>Tumors</subject><subject>Tumors of the nervous system. Phacomatoses</subject><issn>0250-7005</issn><issn>1791-7530</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpF0E1LAzEQBuAgiq3VvyC5iKeFfGyS5qjFqlDx-7ykyaREspua7Fb89y5YEQbmPTwMvHOAplRpWinBySGaEiZIpQgRE3RSygchUuo5P0YTxqjWnMspel6lblP1kFv8OuRd2JmIlynG9BW6DX6BArYPqcPJ4-tsQocfoDdlHCjY59TiJ9PZDKYPFi_GCPkUHXkTC5zt9wy9L2_eFnfV6vH2fnG1qrasJn2lFKNr0JqBlILVzEvmQFLqtGFrpp0VTHlbe0eU1XMtGFHS1cxqT50gbs5n6PL37janzwFK37ShWIjRdJCG0mjKlBa1pqM838th3YJrtjm0Jn83f18YwcUemGJN9HksEsq_E5xTQgn_AV9DZfA</recordid><startdate>20111201</startdate><enddate>20111201</enddate><creator>LEMKE, Johannes</creator><creator>BARTH, Thomas F. E</creator><creator>JUCHEMS, Markus</creator><creator>KAPAPA, Thomas</creator><creator>HENNE-BRUNS, Doris</creator><creator>KORNMANN, Marko</creator><general>International Institute of Anticancer Research</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20111201</creationdate><title>Long-term Survival Following Resection of Brain Metastases from Pancreatic Cancer</title><author>LEMKE, Johannes ; BARTH, Thomas F. E ; JUCHEMS, Markus ; KAPAPA, Thomas ; HENNE-BRUNS, Doris ; KORNMANN, Marko</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p240t-7721be992e665242f62de611d9a2b29dc527fc4fd07c98952076d42c9f1d50d83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Brain Neoplasms - mortality</topic><topic>Brain Neoplasms - secondary</topic><topic>Carcinoma, Pancreatic Ductal - mortality</topic><topic>Carcinoma, Pancreatic Ductal - pathology</topic><topic>Carcinoma, Pancreatic Ductal - surgery</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Neoplasm Metastasis</topic><topic>Neurology</topic><topic>Pancreatic Neoplasms - mortality</topic><topic>Pancreatic Neoplasms - pathology</topic><topic>Pancreatic Neoplasms - surgery</topic><topic>Prognosis</topic><topic>Recurrence</topic><topic>Time Factors</topic><topic>Tomography, X-Ray Computed - methods</topic><topic>Tumors</topic><topic>Tumors of the nervous system. Phacomatoses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>LEMKE, Johannes</creatorcontrib><creatorcontrib>BARTH, Thomas F. E</creatorcontrib><creatorcontrib>JUCHEMS, Markus</creatorcontrib><creatorcontrib>KAPAPA, Thomas</creatorcontrib><creatorcontrib>HENNE-BRUNS, Doris</creatorcontrib><creatorcontrib>KORNMANN, Marko</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Anticancer research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>LEMKE, Johannes</au><au>BARTH, Thomas F. E</au><au>JUCHEMS, Markus</au><au>KAPAPA, Thomas</au><au>HENNE-BRUNS, Doris</au><au>KORNMANN, Marko</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Long-term Survival Following Resection of Brain Metastases from Pancreatic Cancer</atitle><jtitle>Anticancer research</jtitle><addtitle>Anticancer Res</addtitle><date>2011-12-01</date><risdate>2011</risdate><volume>31</volume><issue>12</issue><spage>4599</spage><epage>4603</epage><pages>4599-4603</pages><issn>0250-7005</issn><eissn>1791-7530</eissn><abstract>Brain metastases originating from pancreatic cancer are associated with a dismal prognosis and, generally, therapeutic options remain palliative. We present the cases of two patients that developed brain metastases after resection of a pancreatic ductal adenocarcinoma. Brain metastases were resected successfully and neither patients developed any further tumor recurrence. These cases demonstrate that resection of brain metastatic lesions originating from pancreatic ductal adenocarcinoma is a reasonable therapeutic option with a chance for complete cure in some cases.</abstract><cop>Attiki</cop><pub>International Institute of Anticancer Research</pub><pmid>22199336</pmid><tpages>5</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0250-7005 |
ispartof | Anticancer research, 2011-12, Vol.31 (12), p.4599-4603 |
issn | 0250-7005 1791-7530 |
language | eng |
recordid | cdi_proquest_miscellaneous_912795491 |
source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
subjects | Aged Biological and medical sciences Brain Neoplasms - mortality Brain Neoplasms - secondary Carcinoma, Pancreatic Ductal - mortality Carcinoma, Pancreatic Ductal - pathology Carcinoma, Pancreatic Ductal - surgery Female Humans Male Medical sciences Middle Aged Neoplasm Metastasis Neurology Pancreatic Neoplasms - mortality Pancreatic Neoplasms - pathology Pancreatic Neoplasms - surgery Prognosis Recurrence Time Factors Tomography, X-Ray Computed - methods Tumors Tumors of the nervous system. Phacomatoses |
title | Long-term Survival Following Resection of Brain Metastases from Pancreatic Cancer |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-31T08%3A52%3A27IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Long-term%20Survival%20Following%20Resection%20of%20Brain%20Metastases%20from%20Pancreatic%20Cancer&rft.jtitle=Anticancer%20research&rft.au=LEMKE,%20Johannes&rft.date=2011-12-01&rft.volume=31&rft.issue=12&rft.spage=4599&rft.epage=4603&rft.pages=4599-4603&rft.issn=0250-7005&rft.eissn=1791-7530&rft_id=info:doi/&rft_dat=%3Cproquest_pubme%3E912795491%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=912795491&rft_id=info:pmid/22199336&rfr_iscdi=true |