Differential expression of the β2-adrenoreceptor and M3-cholinoreceptor genes in bronchial mucosa of patients with asthma and chronic obstructive pulmonary disease

Abstract Background Bronchodilators are drugs of choice in the combined therapy of bronchial asthma and chronic obstructive pulmonary disease (COPD). However, the therapeutic sensitivity is variable between patients, probably because of structural features of regulating molecules or variation in key...

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Veröffentlicht in:	Annals of allergy, asthma, & immunology asthma, & immunology, 2012, Vol.108 (1), p.39-43
Hauptverfasser:	Selivanova, Polina A., MD, PhD, Kulikov, Evgeny S., MD, PhD, Kozina, Olga V., MD, PhD, Trofimenko, Irina N., MD, PhD, Freidin, Maxim B., PhD, Chernyak, Boris A., MD, PhD, DSc, Ogorodova, Ludmila M., MD, PhD, DSc
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Allergy and Immunology Asthma - genetics Asthma - metabolism Asthma - physiopathology Bronchi - metabolism Bronchial Hyperreactivity - metabolism Bronchial Hyperreactivity - physiopathology Cross-Sectional Studies Female Humans Male Middle Aged Mucous Membrane - metabolism Pulmonary Disease, Chronic Obstructive - genetics Pulmonary Disease, Chronic Obstructive - metabolism Pulmonary Disease, Chronic Obstructive - physiopathology Receptor, Muscarinic M3 - genetics Receptor, Muscarinic M3 - metabolism Receptors, Adrenergic, beta-2 - genetics Receptors, Adrenergic, beta-2 - metabolism Severity of Illness Index Young Adult
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