Extraskeletal osteosarcoma: spectrum of imaging findings
The purpose of this article is to present the spectrum of imaging findings of primary and metastatic extraskeletal osteosarcoma and highlight the differences from primary osteogenic osteosarcoma in bone. Extraskeletal osteosarcoma is a rare mesenchymal malignancy of soft tissue, histologically indis...
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Veröffentlicht in: | American journal of roentgenology (1976) 2012-01, Vol.198 (1), p.W31-W37 |
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container_title | American journal of roentgenology (1976) |
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creator | Mc Auley, Grainne Jagannathan, Jyothi O'Regan, Kevin Krajewski, Katherine M Hornick, Jason L Butrynski, James Ramaiya, Nikhil |
description | The purpose of this article is to present the spectrum of imaging findings of primary and metastatic extraskeletal osteosarcoma and highlight the differences from primary osteogenic osteosarcoma in bone.
Extraskeletal osteosarcoma is a rare mesenchymal malignancy of soft tissue, histologically indistinguishable from primary osteosarcoma of bone. However, there are distinct differences in demographics, imaging features, prognosis, and management compared with osteogenic osteosarcoma. Imaging characteristics reflect tumor morphology, with only 50% of primary tumors showing mineralization. Metastases may or may not show mineralization, even if present in the primary tumor. The overall prognosis is poor. |
doi_str_mv | 10.2214/AJR.11.6927 |
format | Article |
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Extraskeletal osteosarcoma is a rare mesenchymal malignancy of soft tissue, histologically indistinguishable from primary osteosarcoma of bone. However, there are distinct differences in demographics, imaging features, prognosis, and management compared with osteogenic osteosarcoma. Imaging characteristics reflect tumor morphology, with only 50% of primary tumors showing mineralization. Metastases may or may not show mineralization, even if present in the primary tumor. The overall prognosis is poor.</description><identifier>ISSN: 0361-803X</identifier><identifier>EISSN: 1546-3141</identifier><identifier>DOI: 10.2214/AJR.11.6927</identifier><identifier>PMID: 22194512</identifier><language>eng</language><publisher>United States</publisher><subject>Bone imaging ; Computed tomography ; Contrast Media ; Demography ; Diagnosis, Differential ; Diagnostic Imaging ; Humans ; Malignancy ; Mesenchyme ; Metastases ; Mineralization ; Neoplasm Metastasis ; Osteosarcoma ; Osteosarcoma - diagnosis ; Osteosarcoma - pathology ; Prognosis ; Radiopharmaceuticals ; Soft Tissue Neoplasms - diagnosis ; Soft Tissue Neoplasms - pathology ; Soft tissues ; Tumors</subject><ispartof>American journal of roentgenology (1976), 2012-01, Vol.198 (1), p.W31-W37</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22194512$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mc Auley, Grainne</creatorcontrib><creatorcontrib>Jagannathan, Jyothi</creatorcontrib><creatorcontrib>O'Regan, Kevin</creatorcontrib><creatorcontrib>Krajewski, Katherine M</creatorcontrib><creatorcontrib>Hornick, Jason L</creatorcontrib><creatorcontrib>Butrynski, James</creatorcontrib><creatorcontrib>Ramaiya, Nikhil</creatorcontrib><title>Extraskeletal osteosarcoma: spectrum of imaging findings</title><title>American journal of roentgenology (1976)</title><addtitle>AJR Am J Roentgenol</addtitle><description>The purpose of this article is to present the spectrum of imaging findings of primary and metastatic extraskeletal osteosarcoma and highlight the differences from primary osteogenic osteosarcoma in bone.
Extraskeletal osteosarcoma is a rare mesenchymal malignancy of soft tissue, histologically indistinguishable from primary osteosarcoma of bone. However, there are distinct differences in demographics, imaging features, prognosis, and management compared with osteogenic osteosarcoma. Imaging characteristics reflect tumor morphology, with only 50% of primary tumors showing mineralization. Metastases may or may not show mineralization, even if present in the primary tumor. The overall prognosis is poor.</description><subject>Bone imaging</subject><subject>Computed tomography</subject><subject>Contrast Media</subject><subject>Demography</subject><subject>Diagnosis, Differential</subject><subject>Diagnostic Imaging</subject><subject>Humans</subject><subject>Malignancy</subject><subject>Mesenchyme</subject><subject>Metastases</subject><subject>Mineralization</subject><subject>Neoplasm Metastasis</subject><subject>Osteosarcoma</subject><subject>Osteosarcoma - diagnosis</subject><subject>Osteosarcoma - pathology</subject><subject>Prognosis</subject><subject>Radiopharmaceuticals</subject><subject>Soft Tissue Neoplasms - diagnosis</subject><subject>Soft Tissue Neoplasms - pathology</subject><subject>Soft tissues</subject><subject>Tumors</subject><issn>0361-803X</issn><issn>1546-3141</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1Lw0AYhBdRbK2evEtuekndd9_NbtZbKfWLgiAK3sJ-lmjSxGwC9t8bsV49zeWZYWYIOQc6Zwz49eLxeQ4wF4rJAzKFjIsUgcMhmVIUkOYU3ybkJMZ3SqnMlTwmk9GneAZsSvLVV9_p-OEr3-sqaWLvm6g729T6Jomtt3031EkTkrLWm3K7SUK5daPGU3IUdBX92V5n5PV29bK8T9dPdw_LxTptGcc-1TJzQEEbJgzqQLlGLjwg5ZnKEW3mrBEyE86qYAyCRMedskEGMxb0Oc7I5W9u2zWfg499UZfR-qrSW98MsVDABEeV8ZG8-pcEynIqlcKf0Is9Opjau6Ltxnndrvj7Bb8B7LZjQg</recordid><startdate>201201</startdate><enddate>201201</enddate><creator>Mc Auley, Grainne</creator><creator>Jagannathan, Jyothi</creator><creator>O'Regan, Kevin</creator><creator>Krajewski, Katherine M</creator><creator>Hornick, Jason L</creator><creator>Butrynski, James</creator><creator>Ramaiya, Nikhil</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7QP</scope><scope>7X8</scope></search><sort><creationdate>201201</creationdate><title>Extraskeletal osteosarcoma: spectrum of imaging findings</title><author>Mc Auley, Grainne ; Jagannathan, Jyothi ; O'Regan, Kevin ; Krajewski, Katherine M ; Hornick, Jason L ; Butrynski, James ; Ramaiya, Nikhil</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p243t-a75d101ab26b3af04a346e130459833c5dcb6756dc9fbb3173d4d9cf7fb451e83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Bone imaging</topic><topic>Computed tomography</topic><topic>Contrast Media</topic><topic>Demography</topic><topic>Diagnosis, Differential</topic><topic>Diagnostic Imaging</topic><topic>Humans</topic><topic>Malignancy</topic><topic>Mesenchyme</topic><topic>Metastases</topic><topic>Mineralization</topic><topic>Neoplasm Metastasis</topic><topic>Osteosarcoma</topic><topic>Osteosarcoma - diagnosis</topic><topic>Osteosarcoma - pathology</topic><topic>Prognosis</topic><topic>Radiopharmaceuticals</topic><topic>Soft Tissue Neoplasms - diagnosis</topic><topic>Soft Tissue Neoplasms - pathology</topic><topic>Soft tissues</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mc Auley, Grainne</creatorcontrib><creatorcontrib>Jagannathan, Jyothi</creatorcontrib><creatorcontrib>O'Regan, Kevin</creatorcontrib><creatorcontrib>Krajewski, Katherine M</creatorcontrib><creatorcontrib>Hornick, Jason L</creatorcontrib><creatorcontrib>Butrynski, James</creatorcontrib><creatorcontrib>Ramaiya, Nikhil</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of roentgenology (1976)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mc Auley, Grainne</au><au>Jagannathan, Jyothi</au><au>O'Regan, Kevin</au><au>Krajewski, Katherine M</au><au>Hornick, Jason L</au><au>Butrynski, James</au><au>Ramaiya, Nikhil</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Extraskeletal osteosarcoma: spectrum of imaging findings</atitle><jtitle>American journal of roentgenology (1976)</jtitle><addtitle>AJR Am J Roentgenol</addtitle><date>2012-01</date><risdate>2012</risdate><volume>198</volume><issue>1</issue><spage>W31</spage><epage>W37</epage><pages>W31-W37</pages><issn>0361-803X</issn><eissn>1546-3141</eissn><abstract>The purpose of this article is to present the spectrum of imaging findings of primary and metastatic extraskeletal osteosarcoma and highlight the differences from primary osteogenic osteosarcoma in bone.
Extraskeletal osteosarcoma is a rare mesenchymal malignancy of soft tissue, histologically indistinguishable from primary osteosarcoma of bone. However, there are distinct differences in demographics, imaging features, prognosis, and management compared with osteogenic osteosarcoma. Imaging characteristics reflect tumor morphology, with only 50% of primary tumors showing mineralization. Metastases may or may not show mineralization, even if present in the primary tumor. The overall prognosis is poor.</abstract><cop>United States</cop><pmid>22194512</pmid><doi>10.2214/AJR.11.6927</doi></addata></record> |
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subjects | Bone imaging Computed tomography Contrast Media Demography Diagnosis, Differential Diagnostic Imaging Humans Malignancy Mesenchyme Metastases Mineralization Neoplasm Metastasis Osteosarcoma Osteosarcoma - diagnosis Osteosarcoma - pathology Prognosis Radiopharmaceuticals Soft Tissue Neoplasms - diagnosis Soft Tissue Neoplasms - pathology Soft tissues Tumors |
title | Extraskeletal osteosarcoma: spectrum of imaging findings |
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