Isolation of Sochi Virus From a Fatal Case of Hantavirus Disease With Fulminant Clinical Course

Sochi virus, a novel genetic variant of Dobrava-Belgrade virus, was isolated in cell culture from a fulminant lethal case of hantavirus disease presenting with shock and combined kidney and lung failure. Sochi virus is transmitted to humans from host reservoir Apodemus ponticus and must be considere...

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Veröffentlicht in:Clinical infectious diseases 2012, Vol.54 (1), p.e1-e4
Hauptverfasser: Dzagurova, Tamara K., Witkowski, Peter T., Tkachenko, Evgeniy A., Klempa, Boris, Morozov, Vyacheslav G., Auste, Brita, Zavora, Dmitriy L., Iunicheva, Iulia V., Mutnih, Elena S., Kruger, Detlev H.
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container_issue 1
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container_title Clinical infectious diseases
container_volume 54
creator Dzagurova, Tamara K.
Witkowski, Peter T.
Tkachenko, Evgeniy A.
Klempa, Boris
Morozov, Vyacheslav G.
Auste, Brita
Zavora, Dmitriy L.
Iunicheva, Iulia V.
Mutnih, Elena S.
Kruger, Detlev H.
description Sochi virus, a novel genetic variant of Dobrava-Belgrade virus, was isolated in cell culture from a fulminant lethal case of hantavirus disease presenting with shock and combined kidney and lung failure. Sochi virus is transmitted to humans from host reservoir Apodemus ponticus and must be considered a life-threatening emerging agent. Sochi virus, a novel genetic variant of Dobrava-Belgrade virus, was isolated in cell culture from a fulminant lethal case of hantavirus disease presenting with shock and combined kidney and lung failure. Sochi virus is transmitted to humans from host reservoir Apodemus ponticus and must be considered a life-threatening emerging agent.
doi_str_mv 10.1093/cid/cir746
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subjects Cell culture
Cluster Analysis
Disease
Fatal Outcome
Female
Hantavirus - classification
Hantavirus - genetics
Hantavirus - isolation & purification
Hantavirus Pulmonary Syndrome - complications
Hantavirus Pulmonary Syndrome - mortality
Hantavirus Pulmonary Syndrome - pathology
Hantavirus Pulmonary Syndrome - virology
Hemorrhagic Fever with Renal Syndrome - complications
Hemorrhagic Fever with Renal Syndrome - mortality
Hemorrhagic Fever with Renal Syndrome - pathology
Hemorrhagic Fever with Renal Syndrome - virology
Humans
Medical disorders
Middle Aged
Molecular Sequence Data
Phylogeny
RNA, Viral - genetics
Sequence Analysis, DNA
Viral infections
Virus Cultivation
Viruses
title Isolation of Sochi Virus From a Fatal Case of Hantavirus Disease With Fulminant Clinical Course
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