Comparative study of the plasma globulin level, CD21 − B-cell counts and FOXP3 mRNA expression level in CD4 + T-cells for different clinical stages of feline immunodeficiency virus infected cats

Feline immunodeficiency virus (FIV) infection leads to hypergammaglobulinemia through mechanisms that remain poorly understood. We investigated changes in plasma globulin level, B cells, and T cells with progression of the clinical stage of FIV-infected cats. We classified FIV-infected cats into the...

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Veröffentlicht in:	Research in veterinary science 2012-02, Vol.92 (1), p.157-161
Hauptverfasser:	Takano, Tomomi, Hosoya, Shinobu, Shibao, Akari, Nagasaki, Bunpei, Yoshioka, Hisao, Satoh, Ryoichi, Hohdatsu, Tsutomu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals B-Lymphocytes - metabolism Case-Control Studies Cat Diseases - immunology Cat Diseases - virology Cats CD21 − B-cell CD4-Positive T-Lymphocytes - metabolism Disease Progression Feline Acquired Immunodeficiency Syndrome - immunology FIV Forkhead Transcription Factors - metabolism HIV Human immunodeficiency virus Hypergammaglobulinemia Hypergammaglobulinemia - immunology Hypergammaglobulinemia - veterinary Hypergammaglobulinemia - virology Immunodeficiency Virus, Feline - immunology Lentivirus Infections - immunology Lentivirus Infections - veterinary Lymphocyte Count - veterinary Plasma Proteins Receptors, Complement 3d - metabolism Regulatory T-cell RNA, Messenger - analysis Serum Globulins - metabolism T-Lymphocytes, Regulatory - metabolism Veterinary medicine Viral infections
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