Tenofovir-based pre-exposure prophylaxis for HIV prevention: evolving evidence

PURPOSE OF REVIEWTopical tenofovir gel and oral tenofovir and emtricitabine–tenofovir [FTC/tenofovir disoproxyl fumarate (TDF)] have been demonstrated to have efficacy in preventing HIV-1 in some populations. Preexposure prophylaxis (PrEP) trials and future directions are summarized. RECENT FINDINGS...

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Veröffentlicht in:	Current opinion in infectious diseases 2012-02, Vol.25 (1), p.51-57
Hauptverfasser:	Celum, Connie, Baeten, Jared M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine - analogs & derivatives Adenine - therapeutic use Administration, Oral Administration, Topical Anti-HIV Agents - therapeutic use Female HIV Infections - prevention & control HIV Infections - transmission HIV-1 Humans Male Medication Adherence Organophosphonates - therapeutic use Reverse Transcriptase Inhibitors - therapeutic use Tenofovir
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