Hormone-dependent placental manipulation of breast cancer cell migration

BACKGROUND Breast cancer during pregnancy is often more advanced than in non-pregnant women. Nevertheless, no case of metastasis inside the placenta has been reported. Previously, we showed that placental-explants eliminated breast cancer cells from their surroundings, due to cell-death and elevated...

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Veröffentlicht in:	Human reproduction (Oxford) 2012-01, Vol.27 (1), p.73-88
Hauptverfasser:	Epstein Shochet, G., Tartakover Matalon, S., Drucker, L., Pomeranz, M., Fishman, A., Rashid, G., Oron-Karni, V., Pasmanik-Chor, M., Lishner, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Biological and medical sciences Breast Neoplasms - pathology Cell Line, Tumor Cell Movement Coculture Techniques - methods Estrogens - metabolism Female Gynecology. Andrology. Obstetrics Hormones - metabolism Humans Medical sciences Necrosis Neoplasm Metastasis Oligonucleotide Array Sequence Analysis Placenta - metabolism Placenta - pathology Pregnancy Progesterone - metabolism Signal Transduction
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