DNA Copy Number Alterations in Endobronchial Squamous Metaplastic Lesions Predict Lung Cancer

Autofluorescence bronchoscopy (AFB) is a valid strategy for detecting premalignant endobronchial lesions. However, no biomarker can reliably predict lung cancer risk of subjects with AFB-visualized premalignant lesions. The present study set out to identify AFB-visualized squamous metaplastic (SqM)...

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Veröffentlicht in:	American journal of respiratory and critical care medicine 2011-10, Vol.184 (8), p.948-956
Hauptverfasser:	VAN BOERDONK, Robert A. A, SUTEDJA, Thomas G, MEIJER, Chris J. L. M, MEIJER, Gerrit A, GRÜNBERG, Katrien, DANIELS, Johannes M. A, POSTMUS, Pieter E, SMIT, Egbert F, HEIDEMAN, Daniëlle A. M, SNIJDERS, Peter J. F, REINEN, Emilie, WILTING, Saskia M, VAN DE WIEL, Mark A, THUNNISSEN, F. B. J. M, DUIN, Sylvia, KOOI, Clarissa, YLSTRA, Bauke
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Biopsy Bronchoscopy Carcinoma in Situ - diagnosis Carcinoma in Situ - genetics Carcinoma in Situ - pathology Carcinoma, Squamous Cell - diagnosis Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - pathology Case-Control Studies Clinical death. Palliative care. Organ gift and preservation Cohort Studies DNA Copy Number Variations Female Genetic Markers Humans Intensive care medicine Lung cancer Lung Neoplasms - diagnosis Lung Neoplasms - genetics Lung Neoplasms - pathology Male Medical sciences Metaplasia Middle Aged Risk
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