Effect of a chronic treatment with 17β-estradiol on striatal dopamine neurotransmission and the Akt/GSK3 signaling pathway in the brain of ovariectomized monkeys

Summary The present experiments sought the effect of chronic treatment with 17β-estradiol on striatal dopaminergic activity and the Akt/GSK3 signaling pathway in the brain of monkeys. Eight female monkeys ( Macacca fascicularis ) were ovariectomized (OVX) and a month later, half received a month tre...

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Veröffentlicht in:	Psychoneuroendocrinology 2012-02, Vol.37 (2), p.280-291
Hauptverfasser:	Sánchez, Maria Gabriela, Morissette, Marc, Di Paolo, Thérèse
Format:	Artikel
Sprache:	eng
Schlagworte:	17β-Estradiol Akt/GSK3 signaling Animals Autoradiography Behavioral psychophysiology Biological and medical sciences Caudate Nucleus - diagnostic imaging Dopamine Dopamine - metabolism Dopamine Plasma Membrane Transport Proteins - drug effects Dopamine Plasma Membrane Transport Proteins - metabolism Endocrinology & Metabolism Estradiol - pharmacology Female Fundamental and applied biological sciences. Psychology Glycogen Synthase Kinase 3 - drug effects Glycogen Synthase Kinase 3 - metabolism Hormones and behavior Macaca fascicularis Ovariectomized monkey Ovariectomy Proto-Oncogene Proteins c-akt - drug effects Proto-Oncogene Proteins c-akt - metabolism Psychiatry Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Putamen - diagnostic imaging Radionuclide Imaging Synaptic Transmission - drug effects Vesicular Monoamine Transport Proteins - metabolism
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