Lower Airway Nitric Oxide is Increased in Children with Sickle Cell Disease

Objectives To determine alveolar and airways nitric oxide (NO) levels in children with sickle cell disease (SCD). Study design Multiple flows fractional exhaled NO (FENO ), bronchial NO flux (J’awNO ), and alveolar NO concentration (CaNO ) were determined prospectively in 16 non-atopic children with...

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Veröffentlicht in:	The Journal of pediatrics 2012, Vol.160 (1), p.93-97
Hauptverfasser:	Radhakrishnan, Dhenuka K., MD, Bendiak, Glenda N., MD, Mateos-Corral, Dimas, MD, Al-Saleh, Suhail, MD, Bhattacharjee, Rakesh, MD, Kirby-Allen, Melanie, MD, Grasemann, Hartmut, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Anemia, Sickle Cell - metabolism Anemias. Hemoglobinopathies Biological and medical sciences Bronchi - metabolism Child children Diseases of red blood cells dyskinesia Female General aspects Hematologic and hematopoietic diseases Humans inflammation Male Medical sciences metabolism nitric oxide Nitric Oxide - analysis Nitric Oxide - metabolism Pediatrics Prospective Studies Pulmonary Alveoli - metabolism sickle cell anemia statistical models
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