Asymmetric α-2-tosylethenylation of N,N-dialkyl-L-amino acid esters via the formation of non-racemic ammonium enolates
Asymmetric α-2-tosylethenylation of (S)-2-(pyrrolidin-1-yl)propanoic acid esters was shown to produce good yields with high enantioselectivities. The reaction proceeds via the formation of a non-racemic ammonium enolate without an external source of chirality.
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| Veröffentlicht in: | Organic & biomolecular chemistry 2012-01, Vol.10 (2), p.339-345 |
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| container_end_page | 345 |
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| container_issue | 2 |
| container_start_page | 339 |
| container_title | Organic & biomolecular chemistry |
| container_volume | 10 |
| creator | Tayama, Eiji Igarashi, Tomohito Iwamoto, Hajime Hasegawa, Eietsu |
| description | Asymmetric α-2-tosylethenylation of (S)-2-(pyrrolidin-1-yl)propanoic acid esters was shown to produce good yields with high enantioselectivities. The reaction proceeds via the formation of a non-racemic ammonium enolate without an external source of chirality. |
| doi_str_mv | 10.1039/c1ob06074k |
| format | Article |
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| fulltext | fulltext |
| identifier | EISSN: 1477-0539 |
| ispartof | Organic & biomolecular chemistry, 2012-01, Vol.10 (2), p.339-345 |
| issn | 1477-0539 |
| language | eng |
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| source | MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| subjects | Amino Acids - chemistry Esters - chemistry Molecular Structure Quaternary Ammonium Compounds - chemical synthesis Quaternary Ammonium Compounds - chemistry Stereoisomerism Sulfones - chemistry Toluene - analogs & derivatives Toluene - chemistry |
| title | Asymmetric α-2-tosylethenylation of N,N-dialkyl-L-amino acid esters via the formation of non-racemic ammonium enolates |
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