Small intestine contrast ultrasonography (SICUS) for the detection of small bowel complications in crohn's disease: A prospective comparative study versus intraoperative findings
Background: In Crohn's disease (CD) patients, small intestine contrast ultrasonography (SICUS) accurately assesses small bowel lesions. Its diagnostic role is not known in the assessment of intraabdominal CD complications. The aim was to assess the value of SICUS to detect intestinal complicati...
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| Veröffentlicht in: | Inflammatory bowel diseases 2012-01, Vol.18 (1), p.74-84 |
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| creator | Pallotta, Nadia Vincoli, Giuseppina Montesani, Chiara Chirletti, Piero Pronio, Annamaria Caronna, Roberto Ciccantelli, Barbara Romeo, Erminia Marcheggiano, Adriana Corazziari, Enrico |
| description | Background:
In Crohn's disease (CD) patients, small intestine contrast ultrasonography (SICUS) accurately assesses small bowel lesions. Its diagnostic role is not known in the assessment of intraabdominal CD complications. The aim was to assess the value of SICUS to detect intestinal complications in patients with CD.
Methods:
Forty‐nine CD patients (21 female, mean age 37.7 years; range 12–78 years) underwent resective bowel surgery and were included in this study. The accuracy of SICUS to preoperatively detect number, site, and length of strictures, fistulas, and abscesses was compared with surgical and pathological findings by kappa statistics.
Results:
SICUS identified at least one stricture in 39/40 and excluded it in 9/9 (97.5% sensitivity, 100% specificity, k = 0.93); two or more strictures in 9/12 (75% sensitivity, 100% specificity, k = 0.78). The agreement by k‐statistics between SICUS and surgery in identifying proximal and distal small intestine site of stricture was 1 and 0.92, respectively. The extension of strictures was 6.8 ± 5.4 cm at surgery, 6.6 ± 5.4 cm at SICUS (NS). Fistulas were correctly identified in 27/28 patients and excluded in 19/21 patients (96% sensitivity, 90.5% specificity, k = 0.88). Intraabdominal abscesses were correctly detected in 10/10 patients and excluded in 37/39 patients (100% sensitivity, 95% specificity, k = 0.89).
Conclusions:
SICUS is an accurate method for the detection of small intestinal complications in CD. Noninvasive SICUS is valuable as a primary investigative method for evaluating and planning proper treatment in patients with severe CD of the small bowel. (Inflamm Bowel Dis 2011;) |
| doi_str_mv | 10.1002/ibd.21678 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_911937569</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>911937569</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3598-c10c6069d06ef2483c3471683e096763ae04e90e0ef9a28587f1e0ed8c3112b13</originalsourceid><addsrcrecordid>eNp1kc1u1DAQgC0EoqVw4AWQb6WHtHacODa3svytVInD0nPkdSZdI8cOnqTVvhZPiLO7cEM-zFjzzaexh5C3nF1zxsobt-2uSy4b9Yyc81rIolJV9TznrFEF01qdkVeIPzOaj35JzkpeCcV0fU5-bwbjPXVhApxcAGpjmJLBic5-iTHEh2TG3Z6-36xX95sr2sdEpx3QDiawk4uBxp7iwbKNT-CzYRi9s2apYTZTm-IuXCLtHIJB-EBv6Zgijkv7Ixx4k8whx2nu9vQREs5La54gjnCq9S50Ljzga_KiNx7hzSlekPsvn3-svhV337-uV7d3hRW1VoXlzEomdcck9GWlhBVVw6USwLRspDDAKtAMGPTalKpWTc_zpVNWcF5uubggl0dvHvbXnL-nHRxa8N4EiDO2mnMtmlrqTF4dyfxSxAR9OyY3mLRvOWuXDbV5Q-1hQ5l9d7LO2wG6f-TflWTg5gg8OQ_7_5va9cdPR-UfAhWecw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>911937569</pqid></control><display><type>article</type><title>Small intestine contrast ultrasonography (SICUS) for the detection of small bowel complications in crohn's disease: A prospective comparative study versus intraoperative findings</title><source>MEDLINE</source><source>Access via Wiley Online Library</source><source>Oxford University Press Journals All Titles (1996-Current)</source><creator>Pallotta, Nadia ; Vincoli, Giuseppina ; Montesani, Chiara ; Chirletti, Piero ; Pronio, Annamaria ; Caronna, Roberto ; Ciccantelli, Barbara ; Romeo, Erminia ; Marcheggiano, Adriana ; Corazziari, Enrico</creator><creatorcontrib>Pallotta, Nadia ; Vincoli, Giuseppina ; Montesani, Chiara ; Chirletti, Piero ; Pronio, Annamaria ; Caronna, Roberto ; Ciccantelli, Barbara ; Romeo, Erminia ; Marcheggiano, Adriana ; Corazziari, Enrico</creatorcontrib><description>Background:
In Crohn's disease (CD) patients, small intestine contrast ultrasonography (SICUS) accurately assesses small bowel lesions. Its diagnostic role is not known in the assessment of intraabdominal CD complications. The aim was to assess the value of SICUS to detect intestinal complications in patients with CD.
Methods:
Forty‐nine CD patients (21 female, mean age 37.7 years; range 12–78 years) underwent resective bowel surgery and were included in this study. The accuracy of SICUS to preoperatively detect number, site, and length of strictures, fistulas, and abscesses was compared with surgical and pathological findings by kappa statistics.
Results:
SICUS identified at least one stricture in 39/40 and excluded it in 9/9 (97.5% sensitivity, 100% specificity, k = 0.93); two or more strictures in 9/12 (75% sensitivity, 100% specificity, k = 0.78). The agreement by k‐statistics between SICUS and surgery in identifying proximal and distal small intestine site of stricture was 1 and 0.92, respectively. The extension of strictures was 6.8 ± 5.4 cm at surgery, 6.6 ± 5.4 cm at SICUS (NS). Fistulas were correctly identified in 27/28 patients and excluded in 19/21 patients (96% sensitivity, 90.5% specificity, k = 0.88). Intraabdominal abscesses were correctly detected in 10/10 patients and excluded in 37/39 patients (100% sensitivity, 95% specificity, k = 0.89).
Conclusions:
SICUS is an accurate method for the detection of small intestinal complications in CD. Noninvasive SICUS is valuable as a primary investigative method for evaluating and planning proper treatment in patients with severe CD of the small bowel. (Inflamm Bowel Dis 2011;)</description><identifier>ISSN: 1078-0998</identifier><identifier>EISSN: 1536-4844</identifier><identifier>DOI: 10.1002/ibd.21678</identifier><identifier>PMID: 21438095</identifier><language>eng</language><publisher>Hoboken: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adolescent ; Adult ; Aged ; Child ; Contrast Media ; Crohn Disease - complications ; Crohn Disease - pathology ; Crohn Disease - surgery ; Crohn's disease ; Female ; Follow-Up Studies ; Humans ; Intestine, Small - diagnostic imaging ; Intestine, Small - pathology ; Male ; Middle Aged ; Prognosis ; Prospective Studies ; small intestine, morphology, pathology ; Ultrasonography ; ultrasonography, SICUS ; Young Adult</subject><ispartof>Inflammatory bowel diseases, 2012-01, Vol.18 (1), p.74-84</ispartof><rights>Copyright © 2011 Crohn's & Colitis Foundation of America, Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3598-c10c6069d06ef2483c3471683e096763ae04e90e0ef9a28587f1e0ed8c3112b13</citedby><cites>FETCH-LOGICAL-c3598-c10c6069d06ef2483c3471683e096763ae04e90e0ef9a28587f1e0ed8c3112b13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fibd.21678$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fibd.21678$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>315,782,786,1419,27931,27932,45581,45582</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21438095$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pallotta, Nadia</creatorcontrib><creatorcontrib>Vincoli, Giuseppina</creatorcontrib><creatorcontrib>Montesani, Chiara</creatorcontrib><creatorcontrib>Chirletti, Piero</creatorcontrib><creatorcontrib>Pronio, Annamaria</creatorcontrib><creatorcontrib>Caronna, Roberto</creatorcontrib><creatorcontrib>Ciccantelli, Barbara</creatorcontrib><creatorcontrib>Romeo, Erminia</creatorcontrib><creatorcontrib>Marcheggiano, Adriana</creatorcontrib><creatorcontrib>Corazziari, Enrico</creatorcontrib><title>Small intestine contrast ultrasonography (SICUS) for the detection of small bowel complications in crohn's disease: A prospective comparative study versus intraoperative findings</title><title>Inflammatory bowel diseases</title><addtitle>Inflamm Bowel Dis</addtitle><description>Background:
In Crohn's disease (CD) patients, small intestine contrast ultrasonography (SICUS) accurately assesses small bowel lesions. Its diagnostic role is not known in the assessment of intraabdominal CD complications. The aim was to assess the value of SICUS to detect intestinal complications in patients with CD.
Methods:
Forty‐nine CD patients (21 female, mean age 37.7 years; range 12–78 years) underwent resective bowel surgery and were included in this study. The accuracy of SICUS to preoperatively detect number, site, and length of strictures, fistulas, and abscesses was compared with surgical and pathological findings by kappa statistics.
Results:
SICUS identified at least one stricture in 39/40 and excluded it in 9/9 (97.5% sensitivity, 100% specificity, k = 0.93); two or more strictures in 9/12 (75% sensitivity, 100% specificity, k = 0.78). The agreement by k‐statistics between SICUS and surgery in identifying proximal and distal small intestine site of stricture was 1 and 0.92, respectively. The extension of strictures was 6.8 ± 5.4 cm at surgery, 6.6 ± 5.4 cm at SICUS (NS). Fistulas were correctly identified in 27/28 patients and excluded in 19/21 patients (96% sensitivity, 90.5% specificity, k = 0.88). Intraabdominal abscesses were correctly detected in 10/10 patients and excluded in 37/39 patients (100% sensitivity, 95% specificity, k = 0.89).
Conclusions:
SICUS is an accurate method for the detection of small intestinal complications in CD. Noninvasive SICUS is valuable as a primary investigative method for evaluating and planning proper treatment in patients with severe CD of the small bowel. (Inflamm Bowel Dis 2011;)</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Child</subject><subject>Contrast Media</subject><subject>Crohn Disease - complications</subject><subject>Crohn Disease - pathology</subject><subject>Crohn Disease - surgery</subject><subject>Crohn's disease</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Intestine, Small - diagnostic imaging</subject><subject>Intestine, Small - pathology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Prognosis</subject><subject>Prospective Studies</subject><subject>small intestine, morphology, pathology</subject><subject>Ultrasonography</subject><subject>ultrasonography, SICUS</subject><subject>Young Adult</subject><issn>1078-0998</issn><issn>1536-4844</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kc1u1DAQgC0EoqVw4AWQb6WHtHacODa3svytVInD0nPkdSZdI8cOnqTVvhZPiLO7cEM-zFjzzaexh5C3nF1zxsobt-2uSy4b9Yyc81rIolJV9TznrFEF01qdkVeIPzOaj35JzkpeCcV0fU5-bwbjPXVhApxcAGpjmJLBic5-iTHEh2TG3Z6-36xX95sr2sdEpx3QDiawk4uBxp7iwbKNT-CzYRi9s2apYTZTm-IuXCLtHIJB-EBv6Zgijkv7Ixx4k8whx2nu9vQREs5La54gjnCq9S50Ljzga_KiNx7hzSlekPsvn3-svhV337-uV7d3hRW1VoXlzEomdcck9GWlhBVVw6USwLRspDDAKtAMGPTalKpWTc_zpVNWcF5uubggl0dvHvbXnL-nHRxa8N4EiDO2mnMtmlrqTF4dyfxSxAR9OyY3mLRvOWuXDbV5Q-1hQ5l9d7LO2wG6f-TflWTg5gg8OQ_7_5va9cdPR-UfAhWecw</recordid><startdate>201201</startdate><enddate>201201</enddate><creator>Pallotta, Nadia</creator><creator>Vincoli, Giuseppina</creator><creator>Montesani, Chiara</creator><creator>Chirletti, Piero</creator><creator>Pronio, Annamaria</creator><creator>Caronna, Roberto</creator><creator>Ciccantelli, Barbara</creator><creator>Romeo, Erminia</creator><creator>Marcheggiano, Adriana</creator><creator>Corazziari, Enrico</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201201</creationdate><title>Small intestine contrast ultrasonography (SICUS) for the detection of small bowel complications in crohn's disease: A prospective comparative study versus intraoperative findings</title><author>Pallotta, Nadia ; Vincoli, Giuseppina ; Montesani, Chiara ; Chirletti, Piero ; Pronio, Annamaria ; Caronna, Roberto ; Ciccantelli, Barbara ; Romeo, Erminia ; Marcheggiano, Adriana ; Corazziari, Enrico</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3598-c10c6069d06ef2483c3471683e096763ae04e90e0ef9a28587f1e0ed8c3112b13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Child</topic><topic>Contrast Media</topic><topic>Crohn Disease - complications</topic><topic>Crohn Disease - pathology</topic><topic>Crohn Disease - surgery</topic><topic>Crohn's disease</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Intestine, Small - diagnostic imaging</topic><topic>Intestine, Small - pathology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Prognosis</topic><topic>Prospective Studies</topic><topic>small intestine, morphology, pathology</topic><topic>Ultrasonography</topic><topic>ultrasonography, SICUS</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pallotta, Nadia</creatorcontrib><creatorcontrib>Vincoli, Giuseppina</creatorcontrib><creatorcontrib>Montesani, Chiara</creatorcontrib><creatorcontrib>Chirletti, Piero</creatorcontrib><creatorcontrib>Pronio, Annamaria</creatorcontrib><creatorcontrib>Caronna, Roberto</creatorcontrib><creatorcontrib>Ciccantelli, Barbara</creatorcontrib><creatorcontrib>Romeo, Erminia</creatorcontrib><creatorcontrib>Marcheggiano, Adriana</creatorcontrib><creatorcontrib>Corazziari, Enrico</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Inflammatory bowel diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pallotta, Nadia</au><au>Vincoli, Giuseppina</au><au>Montesani, Chiara</au><au>Chirletti, Piero</au><au>Pronio, Annamaria</au><au>Caronna, Roberto</au><au>Ciccantelli, Barbara</au><au>Romeo, Erminia</au><au>Marcheggiano, Adriana</au><au>Corazziari, Enrico</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Small intestine contrast ultrasonography (SICUS) for the detection of small bowel complications in crohn's disease: A prospective comparative study versus intraoperative findings</atitle><jtitle>Inflammatory bowel diseases</jtitle><addtitle>Inflamm Bowel Dis</addtitle><date>2012-01</date><risdate>2012</risdate><volume>18</volume><issue>1</issue><spage>74</spage><epage>84</epage><pages>74-84</pages><issn>1078-0998</issn><eissn>1536-4844</eissn><abstract>Background:
In Crohn's disease (CD) patients, small intestine contrast ultrasonography (SICUS) accurately assesses small bowel lesions. Its diagnostic role is not known in the assessment of intraabdominal CD complications. The aim was to assess the value of SICUS to detect intestinal complications in patients with CD.
Methods:
Forty‐nine CD patients (21 female, mean age 37.7 years; range 12–78 years) underwent resective bowel surgery and were included in this study. The accuracy of SICUS to preoperatively detect number, site, and length of strictures, fistulas, and abscesses was compared with surgical and pathological findings by kappa statistics.
Results:
SICUS identified at least one stricture in 39/40 and excluded it in 9/9 (97.5% sensitivity, 100% specificity, k = 0.93); two or more strictures in 9/12 (75% sensitivity, 100% specificity, k = 0.78). The agreement by k‐statistics between SICUS and surgery in identifying proximal and distal small intestine site of stricture was 1 and 0.92, respectively. The extension of strictures was 6.8 ± 5.4 cm at surgery, 6.6 ± 5.4 cm at SICUS (NS). Fistulas were correctly identified in 27/28 patients and excluded in 19/21 patients (96% sensitivity, 90.5% specificity, k = 0.88). Intraabdominal abscesses were correctly detected in 10/10 patients and excluded in 37/39 patients (100% sensitivity, 95% specificity, k = 0.89).
Conclusions:
SICUS is an accurate method for the detection of small intestinal complications in CD. Noninvasive SICUS is valuable as a primary investigative method for evaluating and planning proper treatment in patients with severe CD of the small bowel. (Inflamm Bowel Dis 2011;)</abstract><cop>Hoboken</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>21438095</pmid><doi>10.1002/ibd.21678</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Access via Wiley Online Library; Oxford University Press Journals All Titles (1996-Current) |
| subjects | Adolescent Adult Aged Child Contrast Media Crohn Disease - complications Crohn Disease - pathology Crohn Disease - surgery Crohn's disease Female Follow-Up Studies Humans Intestine, Small - diagnostic imaging Intestine, Small - pathology Male Middle Aged Prognosis Prospective Studies small intestine, morphology, pathology Ultrasonography ultrasonography, SICUS Young Adult |
| title | Small intestine contrast ultrasonography (SICUS) for the detection of small bowel complications in crohn's disease: A prospective comparative study versus intraoperative findings |
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