FLT3 mutation and expression did not adversely affect clinical outcome of childhood acute leukaemia-a study of 531 Southeast Asian children by the Ma-Spore study group

FMS‐like tyrosine kinase 3 (FLT3) is critical for normal haematopoiesis and have been reported to be expressed in the majority of acute myeloid and lymphoid malignancies. We correlated the impact of FLT3 mutations and its expression with age, WHO 2008 classification and treatment outcome in 531 chil...

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Veröffentlicht in:Hematological oncology 2011-12, Vol.29 (4), p.211-219
Hauptverfasser: Leow, Shuangjie, Kham, Shirley Kow-Yin, Ariffin, Hany, Quah, Thuan Chong, Yeoh, Allen Eng-Juh
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Sprache:eng
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